Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL5029340 | 0.95 | HIF1A (0.52) | HIF1AALDH1A1TSHRCYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL8086728 | 0.95 | HIF1A (0.52) | HIF1AALDH1A1TSHRCYP1A2CYP2D6 | |
| Phosphine SCHEMBL28055000 | 0.93 | HIF1A (0.50) | HIF1AALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL8378542 | 0.89 | HIF1A (0.46) | HIF1AALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL8606124 | 0.89 | HIF1A (0.46) | HIF1AALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL8376846 | 0.89 | HIF1A (0.46) | HIF1AALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL8374701 | 0.89 | HIF1A (0.46) | HIF1AALDH1A1TSHRCYP1A2CYP2D6 | |
| Bromide SCHEMBL11868606 | 0.80 | HIF1A (0.40) | HIF1AALDH1A1TSHRCYP2D6CYP3A4 | |
| Bromide SCHEMBL9004461 | 0.79 | HIF1A (0.46) | HIF1AALDH1A1TSHRCYP1A2CYP2D6 | |
| Bromide SCHEMBL42887 | 0.79 | HIF1A (0.57) | HIF1AALDH1A1TSHRCYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 247 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743574-B1 | Migration imaging members | XEROX CORP (US) | 2000-12-27 | — | — | EP | claimed |
| EP-0743573-B1 | Method for obtaining image contrast migration imaging members | XEROX CORP (US) | 2000-09-06 | — | — | EP | claimed |
| US-5760809-A | INK JET PRINTING | XEROX CORPORATION (US) | 1998-06-02 | — | — | US | claimed |
| US-5658671-A | ARTICLE COATED WITH COMPOSITION COMPRISING FLUOROELASTOMER, QUATERNARY AMMONIUM OR PHOSPHONIUM ACCELERATOR, POLYOL, ACID ACCEPTOR, OIL-SOLUBLE CHELATING AGENT, ORGANIC SOLVENT | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1997-08-19 | — | — | US | claimed |
| EP-0743574-A2 | Migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0743573-A2 | Method for obtaining image contrast migration imaging members | XEROX CORPORATION (US) | 1996-11-20 | — | — | EP | claimed |
| EP-0615853-B1 | Recording sheets containing phosphonium compounds | XEROX CORP (US) | 1996-10-16 | — | — | EP | claimed |
| US-5563014-A | SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT | XEROX CORPORATION (US) | 1996-10-08 | — | — | US | claimed |
| US-5514505-A | SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE | XEROX CORPORATION (US) | 1996-05-07 | — | — | US | claimed |
| US-5451625-A | FOR USE IN THE PREPARATION OF AUTOMOTIVE GASKETS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-09-19 | — | — | US | claimed |
| EP-0615853-A1 | Recording sheets containing phosphonium compounds | XEROX CORPORATION (US) | 1994-09-21 | — | — | EP | claimed |
| EP-0574319-A1 | Fluoroelastomer coating composition | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-12-15 | — | — | EP | claimed |
| CN-122094937-A | Cannabinoid compounds and uses thereof | — | 2026-05-26 | — | — | CN | disclosed |
| WO-2025078811-A1 | CANNABINOID COMPOUNDS AND USES THEREOF | JAZZ PHARMACEUTICALS RESEARCH UK LIMITED (GB) | 2025-04-17 | — | — | WO | disclosed |
| US-12187681-B2 | Ion channel antagonists/blockers and uses thereof | SHANGHAI EAST HOSPITAL (CN) | 2025-01-07 | — | — | US | disclosed |
| US-20240398828-A1 | HETERO-ATOM CONTAINING COMPOUNDS AND USES THEREOF | KUMQUAT BIOSCIENCES INC. | 2024-12-05 | — | — | US | disclosed |
| EP-0068551-B1 | NON-NUTRITIVE SWEETENERS | THE PROCTER & GAMBLE COMPANY (US) | 1984-11-14 | — | — | EP | disclosed |
| US-4423029-A | (S)-3-Amino-4-[(S,S)-1-(1-hydroxyethyl)alkyl amino]-4-oxo-butyric acid compounds suitable as non-nutritive sweetners | THE PROCTER & GAMBLE COMPANY (US) | 1983-12-27 | — | — | US | disclosed |
| EP-0068551-A1 | Non-nutritive sweeteners | THE PROCTER & GAMBLE COMPANY (US) | 1983-01-05 | — | — | EP | disclosed |
| US-4267363-A | Intermediates for a sex pheramone for yellow scale | ZOECON CORPORATION (US) | 1981-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240398828-A1 | HETERO-ATOM CONTAINING COMPOUNDS AND USES THEREOF | CD74, HLA-DRB1, CD47 | CHRM2 3052/4885CHRM1 4183/4885CHRM3 2384/4885 |
| US-12187681-B2 | Ion channel antagonists/blockers and uses thereof | CACNA1F, CACNA1S, CACNA1D | CHRM2 692/4885CHRM1 793/4885CHRM3 514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.