Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 3/20 | 0.70 |
| ▸ | F2 | P00734 | 1/20 | 0.70 |
| ▸ | F10 | P00742 | 1/20 | 0.70 |
| ▸ | PLAT | P00750 | 1/20 | 0.70 |
| ▸ | FADS1 | O60427 | 1/20 | 0.60 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.57 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | PKM | P14618 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | CASP3 | P42574 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18290068 | 0.79 | P2RX1 (0.80) | PLAUF2F10PLATFADS1 | |
| SCHEMBL330733 | 0.79 | FADS1 (0.78) | PLAUF2F10PLATFADS1 | |
| SCHEMBL16148352 | 0.79 | TMPRSS4 (0.63) | P2RX1TMPRSS4MEN1KMT2AKLKB1 | |
| SCHEMBL8401870 | 0.78 | TMPRSS4 (0.81) | PLAUF2F10PLATFADS1 | |
| SCHEMBL25347627 | 0.77 | FADS1 (0.68) | PLAUF2F10PLATFADS1 | |
| SCHEMBL10272284 | 0.77 | MEN1 (0.74) | P2RX1TMPRSS4MEN1KMT2AALDH1A1 | |
| SCHEMBL14363181 | 0.77 | NPC1 (0.66) | PLAUF2F10PLATFADS1 | |
| SCHEMBL17779225 | 0.76 | NPC1 (0.64) | PLAUF2F10PLATFADS1 | |
| SCHEMBL9609319 | 0.76 | CA1 (0.56) | PLAUF2F10PLATFADS1 | |
| SCHEMBL14363286 | 0.76 | PLAU (0.69) | PLAUF2F10PLATP2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014165816-A1 | COMPOUNDS USEFUL FOR THE TREATMENT OF METABOLIC DISORDERS AND SYNTHESIS OF THE SAME | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2014-10-09 | — | — | WO | disclosed |