Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNK2 | Q07912 | 3/20 | 0.46 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | DHFR | P00374 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | FURIN | P09958 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ACP1 | P24666 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14852899 | 1.00 | TNK2 (0.46) | TNK2NFE2L2DHFRMEN1KMT2A | |
| SCHEMBL3500438 | 0.91 | TNK2 (0.44) | TNK2DHFRMEN1KMT2AHSD11B1 | |
| SCHEMBL15093765 | 0.82 | MEN1 (0.43) | TNK2DHFRMEN1KMT2AHSD11B1 | |
| SCHEMBL5535757 | 0.82 | TNK2 (0.40) | TNK2DHFRMEN1KMT2AHSD11B1 | |
| SCHEMBL674989 | 0.82 | TNK2 (0.40) | TNK2DHFRMEN1KMT2AHSD11B1 | |
| SCHEMBL222919 | 0.82 | MEN1 (0.43) | TNK2DHFRMEN1KMT2AHSD11B1 | |
| SCHEMBL8080838 | 0.82 | TNK2 (0.40) | TNK2DHFRMEN1KMT2AHSD11B1 | |
| SCHEMBL813805 | 0.82 | NPC1 (0.46) | TNK2DHFRMEN1KMT2AHSD11B1 | |
| SCHEMBL12269239 | 0.82 | TNK2 (0.40) | TNK2DHFRMEN1KMT2AHSD11B1 | |
| SCHEMBL8434147 | 0.82 | TNK2 (0.40) | TNK2DHFRMEN1KMT2AHSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3892618-A1 | 4-PYRIDINYL FORMAMIDE COMPOUND OR DERIVATIVE THEREOF, PREPARATION METHOD THEREFOR, HERBICIDAL COMPOSITION AND USE THEREOF | Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) | 2021-10-13 | — | — | EP | disclosed |
| EP-2981530-B1 | ENHANCED OSTEOGENIC ACTIVITY OF DAIDZEIN ANALOGS ON HUMAN MESENCHYMAL STEM CELLS | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2020-02-12 | — | — | EP | disclosed |
| US-20180057444-A1 | AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-03-01 | — | — | US | disclosed |
| US-20180057444-A1 | AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-03-01 | — | — | US | disclosed |
| US-20160068542-A1 | Enhanced Osteogenic Activity of Daidzein Analogs on Human Mesenchymal Stem Cells | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2016-03-10 | — | — | US | disclosed |
| EP-2981530-A2 | ENHANCED OSTEOGENIC ACTIVITY OF DAIDZEIN ANALOGS ON HUMAN MESENCHYMAL STEM CELLS | The Administrators of the Tulane Educational Fund (US) | 2016-02-10 | — | — | EP | disclosed |
| WO-2014165723-A2 | ENHANCED OSTEOGENIC ACTIVITY OF DAIDZEIN ANALOGS ON HUMAN MESENCHYMAL STEM CELLS | THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) | 2014-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180057444-A1 | AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS | AHR, TYR, CYP1A1 | TNK2 2604/4885NFE2L2 136/4885DHFR 1091/4885 |
| US-20160068542-A1 | Enhanced Osteogenic Activity of Daidzein Analogs on Human Mesenchymal Stem Cells | HPGDS, CXCL12, ALPG | TNK2 315/4885NFE2L2 63/4885DHFR 3994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.