SCHEMBL222919

SCHEMBL222919

Oc1ccc(OC2CCCCO2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
HSD11B1 P28845 1/20 0.42
TNK2 Q07912 3/20 0.40
PTPN1 P18031 1/20 0.40
DHFR P00374 1/20 0.38
CA12 O43570 2/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
CA9 Q16790 2/20 0.37
ALDH1A1 P00352 1/20 0.37
KDM4C Q9H3R0 1/20 0.36
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
NPY1R P25929 1/20 0.35
NPY2R P49146 1/20 0.35
NPY4R P50391 1/20 0.35
NPY5R Q15761 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15093959 1.00 MEN1 (0.43) MEN1KMT2AHSD11B1TNK2PTPN1
SCHEMBL15093765 1.00 MEN1 (0.43) MEN1KMT2AHSD11B1TNK2PTPN1
SCHEMBL217929 0.95 TNK2 (0.43) MEN1KMT2AHSD11B1TNK2PTPN1
SCHEMBL7155013 0.95 ALDH1A1 (0.41) MEN1KMT2AHSD11B1TNK2PTPN1
SCHEMBL15214980 0.95 ALDH1A1 (0.41) MEN1KMT2AHSD11B1TNK2PTPN1
SCHEMBL15214979 0.95 ALDH1A1 (0.41) MEN1KMT2AHSD11B1TNK2PTPN1
SCHEMBL16055037 0.92 HSD11B1 (0.41) MEN1KMT2AHSD11B1TNK2PTPN1
SCHEMBL21400657 0.91 APP (0.44) MEN1KMT2AHSD11B1TNK2PTPN1
SCHEMBL3500438 0.91 TNK2 (0.44) MEN1KMT2AHSD11B1TNK2DHFR
SCHEMBL28981248 0.89 CALM1 (0.41) MEN1KMT2AHSD11B1TNK2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118750401-A Composition for improving mitochondrial function, care product and application 深圳市护家科技有限公司 2024-10-11 CN claimed
WO-2024165901-A1 BENZO[b]SELENOPHENES AS NOVEL SELECTIVE ESTROGEN RECEPTOR MODULATORS LATVIAN INSTITUTE OF ORGANIC SYNTHESIS (LV) 2024-08-15 WO claimed
EP-3335694-B1 MELANOGENESIS INHIBITOR TAKASAGO PERFUMERY CO LTD (JP) 2023-09-27 EP claimed
CN-112121223-B Sericin medical dressing and production method thereof 河南民兴生物科技股份有限公司 2022-05-20 CN claimed
WO-2022092639-A1 STABILIZATION COMPOSITION INCLUDING HYDROQUINONE OR DERIVATIVE THEREOF 주식회사 엘지생활건강 2022-05-05 WO claimed
CN-114425024-A Stabilized compositions containing hydroquinone or derivatives thereof 株式会社LG生活健康 2022-05-03 CN claimed
EP-3212688-B1 THERMOPLASTIC POLYURETHANE FILM FOR DELIVERY OF ACTIVE AGENTS TO SKIN SURFACES LUBRIZOL ADVANCED MAT INC (US) 2022-04-13 EP claimed
US-9708287-B2 Chiral compounds, compositions, products and methods employing same CAYMAN CHEMICAL COMPANY INCORPORATED (US) 2017-07-18 US claimed
US-9180080-B2 Chiral compounds, compositions, products and methods employing same MERZ NORTH AMERICA, INC. (US) 2015-11-10 US claimed
EP-2800470-A1 SKIN LIGHTENING COMPOSITIONS Merz North America, Inc. (US) 2014-11-12 EP claimed
US-20130224137-A1 SKIN LIGHTENING COMPOSITIONS LASYA, INC. (US) 2013-08-29 US claimed
WO-2013103874-A1 SKIN LIGHTENING COMPOSITIONS LASYA, INC. (US) 2013-07-11 WO claimed
EP-0748307-B1 SKIN LIGHTENING COMPOSITIONS PROCTER & GAMBLE (US) 2001-12-12 EP claimed
US-6068834-A ORALLY ADMINISTERING A MELANINS REDUCING OXY PHENOL COMPOUND TO THE MAMMAL FOR LIGHTENING THE MAMMALIAN SKIN; TYROSINASE INHIBITOR THE PROCTER & GAMBLE COMPANY (US) 2000-05-30 US claimed
EP-0748307-A1 SKIN LIGHTENING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1996-12-18 EP claimed
WO-1995023780-A2 SKIN LIGHTENING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1995-09-08 WO claimed
JP-6192062-A None JP disclosed
WO-2026104315-A1 TOPICAL SKIN CARE COMPOSITIONS WITH C16:1 FATTY ACID UNILEVER IP HOLDINGS B.V. (NL) 2026-05-21 WO disclosed
JP-H06192062-A DERMAL EXTERNAL PREPARATION SHISEIDO CO LTD 1994-07-12 JP disclosed
EP-0383319-A2 Imidazopyridines, their production and use Takeda Chemical Industries, Ltd. (JP) 1990-08-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130224137-A1 SKIN LIGHTENING COMPOSITIONS CUTA, COL14A1, COLGALT1 MEN1 3556/4885KMT2A 4262/4885HSD11B1 1544/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.