Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.53 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.53 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.53 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.53 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.53 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.51 |
| ▸ | TPH1 | P17752 | 2/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.46 |
| ▸ | KIF11 | P52732 | 3/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7453651 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GRIA1GRIA2GRIA3 | |
| SCHEMBL16148363 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2GRIA1GRIA2GRIA3 | |
| SCHEMBL20438857 | 0.89 | GRIK1 (0.54) | GRIK1GRIK2GRIA1GRIA2GRIA3 | |
| SCHEMBL25356342 | 0.83 | GRIK1 (0.54) | GRIK1GRIK2GRIA1GRIA2GRIA3 | |
| SCHEMBL1768639 | 0.83 | SLC7A5 (0.67) | GRIK1GRIK2GRIA1GRIA2GRIA3 | |
| SCHEMBL3629108 | 0.83 | GRIK1 (0.54) | GRIK1GRIK2GRIA1GRIA2GRIA3 | |
| SCHEMBL1666620 | 0.83 | SLC7A5 (0.67) | GRIK1GRIK2GRIA1GRIA2GRIA3 | |
| SCHEMBL6377896 | 0.83 | GRIK1 (0.54) | GRIK1GRIK2GRIA1GRIA2GRIA3 | |
| SCHEMBL3629107 | 0.83 | GRIK1 (0.54) | GRIK1GRIK2GRIA1GRIA2GRIA3 | |
| SCHEMBL9394667 | 0.83 | SLC7A5 (0.67) | GRIK1GRIK2GRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | claimed |
| EP-4554959-A2 | COMPOSITIONS INCLUDING MULTI-AGONIST PEPTIDES AND METHODS OF MANUFACTURE AND USE | Pep2Tango Therapeutics Inc. (US) | 2025-05-21 | — | — | EP | disclosed |
| WO-2024148312-A1 | COMPOSITIONS, SYSTEMS, AND METHODS FOR AMINO ACID SYNTHESIS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-07-11 | — | — | WO | disclosed |
| EP-4370537-A1 | COMPOSITIONS INCLUDING MULTI-AGONIST PEPTIDES AND METHODS OF MANUFACTURE AND USE | Pep2Tango Therapeutics Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| WO-2024015922-A2 | COMPOSITIONS INCLUDING MULTI-AGONIST PEPTIDES AND METHODS OF MANUFACTURE AND USE | PEP2TANGO THERAPEUTICS INC. (US) | 2024-01-18 | — | — | WO | disclosed |
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | disclosed |
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | disclosed |
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2023-08-17 | — | — | US | disclosed |
| WO-2023288313-A1 | COMPOSITIONS INCLUDING MULTI-AGONIST PEPTIDES AND METHODS OF MANUFACTURE AND USE | PEP2TANGO THERAPEUTICS INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| EP-3218392-B1 | MACROCYCLIC PEPTIDES USEFUL AS IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2020-07-29 | — | — | EP | disclosed |
| EP-3626732-A1 | MACROCYCLIC INHIBITORS OF THE PD-1/PD-L1 AND CD80(B7-1)/PD-L1 PROTEIN/PROTEIN INTERACTIONS | Bristol-Myers Squibb Company (US) | 2020-03-25 | — | — | EP | disclosed |
| US-10344060-B2 | Potent and selective inhibitors of Nav1.7 | AMGEN INC. (US) | 2019-07-09 | — | — | US | disclosed |
| EP-2970408-B1 | POTENT AND SELECTIVE INHIBITORS OF NAV1.7 | AMGEN INC (US) | 2018-01-10 | — | — | EP | disclosed |
| US-20160024159-A1 | POTENT AND SELECTIVE INHIBITORS OF NAV1.7 | AMGEN INC. (US) | 2016-01-28 | — | — | US | disclosed |
| EP-2970408-A2 | POTENT AND SELECTIVE INHIBITORS OF Nav1.7 | Amgen Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014165277-A2 | POTENT AND SELECTIVE INHIBITORS OF Nav1.7 | AMGEN INC. (US) | 2014-10-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10344060-B2 | Potent and selective inhibitors of Nav1.7 | SCN7A, SCN9A, SCN1A | GRIK1 404/4885GRIK2 415/4885GRIA1 994/4885 |
| US-20230257343-A1 | NOVEL AMINO ACID DERIVATIVES | DNPEP, BCAT1, ANPEP | GRIK1 3246/4885GRIK2 3097/4885GRIA1 2495/4885 |
| US-20160024159-A1 | POTENT AND SELECTIVE INHIBITORS OF NAV1.7 | SCN7A, SCN9A, SCN1A | GRIK1 404/4885GRIK2 415/4885GRIA1 994/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.