Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 4/20 | 0.58 |
| ▸ | TP53 | P04637 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | FADS1 | O60427 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24481190 | 0.84 | KCNMA1 (0.68) | KCNMA1LMNANPC1HTTTP53 | |
| SCHEMBL17413293 | 0.83 | KCNMA1 (0.65) | KCNMA1LMNANPC1HTTTP53 | |
| SCHEMBL2701801 | 0.82 | HPGD (0.77) | KCNMA1LMNANPC1HTTTP53 | |
| SCHEMBL20415511 | 0.80 | KCNMA1 (0.66) | KCNMA1LMNANPC1HTTTP53 | |
| SCHEMBL29936061 | 0.79 | KCNMA1 (0.78) | KCNMA1LMNANPC1HTTTP53 | |
| SCHEMBL4264455 | 0.79 | KCNMA1 (0.78) | KCNMA1LMNANPC1HTTTP53 | |
| SCHEMBL16147168 | 0.78 | P2RX1 (0.51) | KCNMA1LMNANPC1HTTTP53 | |
| SCHEMBL23847728 | 0.78 | KCNMA1 (0.52) | KCNMA1LMNANPC1HTTTP53 | |
| SCHEMBL11692515 | 0.78 | KCNMA1 (0.58) | KCNMA1LMNANPC1HTTTP53 | |
| SCHEMBL16148191 | 0.77 | PYGL (0.51) | KCNMA1LMNANPC1HTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014165816-A1 | COMPOUNDS USEFUL FOR THE TREATMENT OF METABOLIC DISORDERS AND SYNTHESIS OF THE SAME | NORTH CAROLINA CENTRAL UNIVERSITY (US) | 2014-10-09 | — | — | WO | disclosed |