SCHEMBL17728069

SCHEMBL17728069

CNCOC[C@H]1O[C@@H](n2ccc(=O)[nH]c2=S)[C@H](O)[C@@H]1O

nearest known ligand 0.61

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
P2RY14 Q15391 8/20 0.61
P2RY6 Q15077 8/20 0.59
P2RY2 P41231 9/20 0.55
P2RY4 P51582 4/20 0.55
SLC28A1 O00337 1/20 0.50
SLC28A2 O43868 1/20 0.50
SLC29A1 Q99808 1/20 0.50
SLC28A3 Q9HAS3 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6754596 0.89 P2RY14 (0.61) P2RY14P2RY6P2RY2P2RY4SLC28A1
SCHEMBL16148484 0.89 SLC28A1 (0.65) P2RY14P2RY6P2RY2P2RY4SLC28A1
SCHEMBL15515639 0.88 P2RY2 (0.51) P2RY14P2RY6P2RY2P2RY4SLC28A1
SCHEMBL41269 0.85 P2RY14 (0.55) P2RY14P2RY6P2RY2P2RY4SLC28A1
SCHEMBL366853 0.85 P2RY14 (0.55) P2RY14P2RY6P2RY2P2RY4SLC28A1
SCHEMBL7611038 0.85 P2RY14 (0.61) P2RY14P2RY6P2RY2P2RY4SLC28A1
SCHEMBL6028058 0.85 P2RY14 (0.69) P2RY14P2RY6P2RY2P2RY4SLC28A1
SCHEMBL5964450 0.85 P2RY14 (0.61) P2RY14P2RY6P2RY2P2RY4SLC28A1
SCHEMBL17065224 0.85 P2RY14 (0.54) P2RY14P2RY6P2RY2P2RY4SLC28A1
SCHEMBL7516112 0.84 P2RY14 (0.60) P2RY14P2RY6P2RY2P2RY4SLC28A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025125630-A1 METHOD FOR BIOPROTAC DESIGN MEDIMMUNE LIMITED (GB) 2025-06-19 WO disclosed
EP-4298214-A1 NUCLEIC ACID VECTORS AND METHODS OF USE Intergalactic Therapeutics, Inc. (US) 2024-01-03 EP disclosed
WO-2022182795-A1 NUCLEIC ACID VECTORS AND METHODS OF USE Intergalactic Therapeutics, Inc. (US) 2022-09-01 WO disclosed
EP-3668520-A1 MODIFIED MRNA VACCINES ENCODING HERPES SIMPLEX VIRUS GLYCOPROTEINS AND USES THEREOF The Trustees Of The University Of Pennsylvania (US) 2020-06-24 EP disclosed
US-20200140571-A1 INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF METHIONYL-TRNA SYNTHETASES ATYR PHARMA INC (US) 2020-05-07 US disclosed
WO-2019035066-A1 MODIFIED MRNA VACCINES ENCODING HERPES SIMPLEX VIRUS GLYCOPROTEINS AND USES THEREOF THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2019-02-21 WO disclosed
US-20190022100-A1 ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF TRANA DISCOVERY INC (US) 2019-01-24 US disclosed
US-10098887-B2 Antiviral compounds and methods of use thereof TRANA DISCOVERY, INC. (US) 2018-10-16 US disclosed
EP-3364980-A1 NUCLEIC ACID VACCINES FOR VARICELLA ZOSTER VIRUS (VZV) ModernaTX, Inc. (US) 2018-08-29 EP disclosed
WO-2017070601-A1 NUCLEIC ACID VACCINES FOR VARICELLA ZOSTER VIRUS (VZV) MODERNATX, INC. (US) 2017-04-27 WO disclosed
US-20160129006-A1 ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF TRANA DISCOVERY INC (US) 2016-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10098887-B2 Antiviral compounds and methods of use thereof TYMP, MAVS, ZC3HAV1 P2RY14 2463/4885P2RY6 2935/4885P2RY2 3758/4885
US-20160129006-A1 ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF TYMP, MAVS, ZC3HAV1 P2RY14 2463/4885P2RY6 2935/4885P2RY2 3758/4885
US-20190022100-A1 ANTIVIRAL COMPOUNDS AND METHODS OF USE THEREOF TYMP, MAVS, ZC3HAV1 P2RY14 2463/4885P2RY6 2935/4885P2RY2 3758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.