SCHEMBL1614878

SCHEMBL1614878

CCCCOC(=O)C(=Cc1ccccc1)OC

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.51
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
TDP1 Q9NUW8 4/20 0.49
TSHR P16473 4/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
SMN1; SMN2 Q16637 2/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
ALDH1A1 P00352 3/20 0.43
CYP3A4 P08684 2/20 0.43
MAPK1 P28482 2/20 0.43
LMNA P02545 2/20 0.43
TP53 P04637 1/20 0.43
ABCG2 Q9UNQ0 1/20 0.43
HSD17B10 Q99714 1/20 0.42
NR1H4 Q96RI1 1/20 0.42
POLB P06746 2/20 0.42
FAAH O00519 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3460324 0.96 TSHR (0.49) KDM4EMEN1KMT2ATDP1TSHR
SCHEMBL4629242 0.94 LMNA (0.50) KDM4EMEN1KMT2ATDP1TSHR
SCHEMBL15610 0.94 LMNA (0.50) KDM4EMEN1KMT2ATDP1TSHR
SCHEMBL8872482 0.94 LMNA (0.50) KDM4EMEN1KMT2ATDP1TSHR
SCHEMBL6674757 0.94 LMNA (0.50) KDM4EMEN1KMT2ATDP1TSHR
SCHEMBL4421067 0.94 LMNA (0.50) KDM4EMEN1KMT2ATDP1TSHR
SCHEMBL8872228 0.94 LMNA (0.50) KDM4EMEN1KMT2ATDP1TSHR
Acetic Acid SCHEMBL28691928 0.92 TSHR (0.48) KDM4EMEN1KMT2ATDP1TSHR
Alcohol SCHEMBL27701846 0.92 LMNA (0.48) KDM4EMEN1KMT2ATDP1TSHR
SCHEMBL2474894 0.91 MEN1 (0.53) KDM4EMEN1KMT2AL3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3348251-B1 SUNSCREEN COMPOSITIONS GLAXOSMITHKLINE CONSUMER HEALTHCARE HOLDINGS US LLC (US) 2024-01-17 EP disclosed
EP-3348251-A1 SUNSCREEN COMPOSITIONS Wyeth LLC (US) 2018-07-18 EP disclosed
EP-2488151-B1 SUNSCREEN COMPOSITIONS WYETH LLC (US) 2018-02-28 EP disclosed
CN-107108919-A Degradation material and the packaging manufactured by degradation material 蒙诺苏尔有限公司 2017-08-29 CN disclosed
EP-1434562-B1 COSMETIC AND DERMATOLOGICAL STICK BEIERSDORF AG (DE) 2017-08-16 EP disclosed
US-9399008-B2 Sunscreen compositions WYETH LLC (US) 2016-07-26 US disclosed
US-20150305996-A1 SUNSCREEN COMPOSITIONS CONOPCO, INC. 2015-10-29 US disclosed
US-9126059-B2 Sunscreen compositions WYETH LLC (US) 2015-09-08 US disclosed
US-8329200-B2 Water in oil emulsion has moisturizer of glycerol, chitosan, Fucogel, propylene glycol, polyoxyethylene glycol, dipropylene glycol, butylene glycol, mannitol, lactic acid, glycine,, sodium 2-pyrrolidone-5-carboxylate, hyaluronic acid, urea, and/or salts; storage stability; acne, wrinkle resistance BEIERSDORF AG (DE) 2012-12-11 US disclosed
EP-2488151-A2 SUNSCREEN COMPOSITIONS Wyeth LLC (US) 2012-08-22 EP disclosed
WO-2011046919-A2 SUNSCREEN COMPOSITIONS WYETH LLC (US) 2011-04-21 WO disclosed
US-20110085994-A1 Sunscreen Compositions WYETH LLC (US) 2011-04-14 US disclosed
CN-100475798-C Sulfonate derivatives and the use therof as latent acids CIBA SC HOLDING AG (CH) 2009-04-08 CN disclosed
US-7465438-B2 Solubilizing agents/solvents for organic UV filters GOLDSCHMIDT GMBH (DE) 2008-12-16 US disclosed
US-20050232877-A1 Solubilizing agents/solvents for organic UV filters GOLDSCHMIDT GMBH (DE) 2005-10-20 US disclosed
CN-1628268-A Sulfonic acid derivatives and their use as latent acids CIBA SC HOLDING AG (CH) 2005-06-15 CN disclosed
CN-1151197-C Stable metallocene polyolefine �������⻯ѧƷ�ع����޹�˾ 2004-05-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050232877-A1 Solubilizing agents/solvents for organic UV filters APP, BACE1, CBR1 KDM4E 2681/4885MEN1 1555/4885KMT2A 4129/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.