SCHEMBL4070148

SCHEMBL4070148

CCCCCCCCCCCCCCCCCCOC(=O)/C=C/c1ccc(OC)cc1

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
APP P05067 5/20 0.66
TDP1 Q9NUW8 2/20 0.65
GSK3B P49841 1/20 0.55
TAS1R3 Q7RTX0 1/20 0.54
TAS1R1 Q7RTX1 1/20 0.54
F3 P13726 1/20 0.54
ATM Q13315 2/20 0.53
THRB P10828 1/20 0.53
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
HCAR2 Q8TDS4 1/20 0.51
MAPT P10636 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4421069 1.00 LMNA (0.68) LMNASMN1; SMN2APPTDP1GSK3B
SCHEMBL6674756 1.00 LMNA (0.68) LMNASMN1; SMN2APPTDP1GSK3B
SCHEMBL15611 1.00 LMNA (0.68) LMNASMN1; SMN2APPTDP1GSK3B
SCHEMBL8872489 1.00 LMNA (0.68) LMNASMN1; SMN2APPTDP1GSK3B
SCHEMBL8872231 1.00 LMNA (0.68) LMNASMN1; SMN2APPTDP1GSK3B
SCHEMBL4070152 1.00 LMNA (0.68) LMNASMN1; SMN2APPTDP1GSK3B
SCHEMBL59457 1.00 LMNA (0.68) LMNASMN1; SMN2APPTDP1GSK3B
SCHEMBL30746 1.00 LMNA (0.68) LMNASMN1; SMN2APPTDP1GSK3B
SCHEMBL2489079 1.00 LMNA (0.68) LMNASMN1; SMN2APPTDP1GSK3B
Hydrochloric Acid SCHEMBL10437237 0.99 LMNA (0.70) LMNASMN1; SMN2APPTDP1GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3771335-A1 REPELLENT COMPOSITION Athenion AG (CH) 2021-02-03 EP disclosed
EP-3771336-A1 REPELLENT COMPOSITION Athenion AG (CH) 2021-02-03 EP disclosed
US-9314021-B2 Formulations containing insect repellent compounds E I DU PONT DE NEMOURS AND COMPANY (US) 2016-04-19 US disclosed
US-20140288167-A1 Formulations Containing Insect Repellent Compounds E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-09-25 US disclosed
US-8771718-B2 Formulated tick and insect repellent compositions E I DU PONT DE NEMOURS AND COMPANY (US) 2014-07-08 US disclosed
US-8748477-B2 Formulations containing insect repellent compounds E I DU PONT DE NEMOURS AND COMPANY (US) 2014-06-10 US disclosed
CN-101442908-A Formulated tick and insect repellent compositions DU PONT (US) 2009-05-27 CN disclosed
EP-2040555-A2 FORMULATED TICK AND INSECT REPELLENT COMPOSITIONS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2009-04-01 EP disclosed
WO-2007133683-A2 FORMULATED TICK AND INSECT REPELLENT COMPOSITIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-11-22 WO disclosed
US-20070264297-A1 Formulated tick and insect repellent compositions 1,4Group, Inc. 2007-11-15 US disclosed
US-20060223878-A1 Formulations containing insect repellent compounds 1,4Group, Inc. 2006-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140288167-A1 Formulations Containing Insect Repellent Compounds CAT, HNMT, MME LMNA 3157/4885SMN1; SMN2 1636/4885APP 403/4885
US-20060223878-A1 Formulations containing insect repellent compounds CAT, HNMT, MME LMNA 3157/4885SMN1; SMN2 1636/4885APP 403/4885
US-20070264297-A1 Formulated tick and insect repellent compositions MME, FNTA, ACHE LMNA 1412/4885SMN1; SMN2 2231/4885APP 633/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.