Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | PRNP | P04156 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17498740 | 0.91 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1GAAHPGD | |
| SCHEMBL17498776 | 0.83 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1GAAHPGD | |
| SCHEMBL17498808 | 0.83 | MEN1 (0.59) | MEN1KMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL17498728 | 0.78 | ALDH1A1 (0.56) | MEN1KMT2AALDH1A1GAAHSD17B10 | |
| SCHEMBL17498804 | 0.78 | ALDH1A1 (0.60) | KMT2AALDH1A1GAAL3MBTL1SMN1; SMN2 | |
| SCHEMBL27714559 | 0.78 | L3MBTL1 (0.59) | MEN1KMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL17498741 | 0.77 | AURKA (0.42) | ALDH1A1HSD17B10SMN1; SMN2HPGDLMNA | |
| SCHEMBL17498831 | 0.76 | ALDH1A1 (0.58) | ALDH1A1GAASMN1; SMN2HPGDNPSR1 | |
| SCHEMBL16147500 | 0.76 | MEN1 (0.39) | MEN1KMT2AALDH1A1HSD17B10SMN1; SMN2 | |
| SCHEMBL16147231 | 0.76 | LCK (0.38) | ALDH1A1L3MBTL1HSD17B10HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2991644-A2 | NONSTEROIDAL AND STEROIDAL COMPOUNDS WITH POTENT ANDROGEN RECEPTOR DOWN-REGULATION AND ANTI PROSTATE CANCER ACTIVITY | University of Maryland, Baltimore (US) | 2016-03-09 | — | — | EP | disclosed |
| WO-2014165815-A2 | NONSTEROIDAL AND STEROIDAL COMPOUNDS WITH POTENT ANDROGEN RECEPTOR DOWN-REGULATION AND ANTI PROSTATE CANCER ACTIVITY | UNIVERSITY OF MARYLAND, BALTIMORE (US) | 2014-10-09 | — | — | WO | disclosed |