Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.45 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.45 |
| ▸ | LGALS4 | P56470 | 1/20 | 0.45 |
| ▸ | GJB2 | P29033 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.42 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.42 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.42 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.42 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6552389 | 0.92 | GJB2 (0.46) | SLC6A2LGALS8GJB2MAPK1SSTR1 | |
| SCHEMBL6552394 | 0.92 | GJB2 (0.46) | SLC6A2LGALS8GJB2MAPK1SSTR1 | |
| SCHEMBL9800982 | 0.88 | SLC6A2 (0.52) | SLC6A2LGALS8LGALS3MAPK1SSTR1 | |
| SCHEMBL7195901 | 0.87 | SLC6A2 (0.51) | SLC6A2LGALS8GJB2 | |
| SCHEMBL7596317 | 0.87 | SLC6A2 (0.51) | SLC6A2LGALS8GJB2 | |
| SCHEMBL5828864 | 0.87 | SLC6A2 (0.51) | SLC6A2LGALS8GJB2 | |
| SCHEMBL5828861 | 0.87 | SLC6A2 (0.51) | SLC6A2LGALS8GJB2 | |
| SCHEMBL7596323 | 0.87 | SLC6A2 (0.51) | SLC6A2LGALS8GJB2 | |
| SCHEMBL26273937 | 0.84 | SSTR1 (0.53) | GJB2SSTR1SSTR2SSTR4SSTR3 | |
| SCHEMBL7069950 | 0.83 | LGALS8 (0.57) | SLC6A2LGALS8LGALS3SSTR1SSTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981270-A2 | ESTERS OF 2-DEOXY-MONOSACCHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | Board of Regents, The University of Texas System (US) | 2016-02-10 | — | — | EP | disclosed |
| WO-2014165736-A2 | ESTERS OF 2-DEOXY-MONOSACCHARIDES WITH ANTI PROLIFERATIVE ACTIVITY | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2014-10-09 | — | — | WO | disclosed |