Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.46 |
| ▸ | HTR2B | P41595 | 2/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30902367 | 0.88 | MEN1 (0.49) | HTR2CHTR2BSLC6A4HTR6TDP1 | |
| SCHEMBL18783932 | 0.88 | MEN1 (0.49) | HTR2CHTR2BSLC6A4HTR6TDP1 | |
| SCHEMBL7667342 | 0.83 | SLC6A4 (0.51) | HTR2CHTR2BSLC6A4HTR6TDP1 | |
| SCHEMBL28722986 | 0.82 | ALDH1A1 (0.43) | TDP1ERN1 | |
| SCHEMBL28722985 | 0.82 | ALDH1A1 (0.43) | TDP1ERN1 | |
| SCHEMBL5472935 | 0.82 | SLC6A4 (0.53) | HTR2CHTR2BSLC6A4HTR6PTGER1 | |
| SCHEMBL27340554 | 0.81 | HPGD (0.40) | HTR2CHTR2BPTGER1HPGDCNR2 | |
| SCHEMBL5628332 | 0.81 | SLC6A4 (0.55) | HTR2CHTR2BSLC6A4HTR6PTGER1 | |
| SCHEMBL7927301 | 0.80 | ALDH1A1 (0.57) | TDP1MEN1KMT2AERN1HPGD | |
| SCHEMBL15786283 | 0.79 | ERN1 (0.38) | HTR2CTDP1KMT2AERN1PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |
| EP-2968282-A1 | HISTONE DEMENTHYLASE INHIBITORS | Quanticel Pharmaceuticals Inc (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014164708-A1 | HISTONE DEMENTHYLASE INHIBITORS | Quanticel Pharmaceuticals, Inc. (US) | 2014-10-09 | — | — | WO | disclosed |