SCHEMBL27340554

SCHEMBL27340554

O=Cc1cc(Cl)c(Cl)cc1OCC1CC1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.40
KMO O15229 3/20 0.38
CNR2 P34972 9/20 0.37
PTGER1 P34995 1/20 0.36
HTR2C P28335 2/20 0.36
HTR2B P41595 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30933784 0.81 PARP15 (0.38) HTR2CHTR2B
SCHEMBL30902367 0.81 MEN1 (0.49) HPGDPTGER1HTR2CHTR2B
SCHEMBL18783932 0.81 MEN1 (0.49) HPGDPTGER1HTR2CHTR2B
SCHEMBL16150607 0.81 HTR2C (0.46) HPGDCNR2PTGER1HTR2CHTR2B
SCHEMBL28405664 0.80 CNR2 (0.43) KMOCNR2
SCHEMBL7667342 0.76 SLC6A4 (0.51) HPGDPTGER1HTR2CHTR2B
SCHEMBL27340448 0.75 LMNA (0.53) HPGD
SCHEMBL5472935 0.75 SLC6A4 (0.53) HPGDPTGER1HTR2CHTR2B
SCHEMBL17603138 0.75 CNR2 (0.42) KMOCNR2
SCHEMBL28475280 0.75 LMNA (0.37) HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4619097-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2025-09-24 EP disclosed
WO-2025106477-A1 NOVEL AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2025-05-22 WO disclosed
WO-2024107434-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2024-05-23 WO disclosed
WO-2024107434-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2024-05-23 WO disclosed