Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12506125 | 0.86 | GPR119 (0.71) | GPR119CYP3A4CYP2C19 | |
| SCHEMBL14160288 | 0.74 | GPR119 (0.62) | GPR119CYP3A4CYP2C19CNR2SCN9A | |
| SCHEMBL12506069 | 0.72 | GPR119 (0.79) | GPR119CYP3A4CYP2C19CNR2SCN9A | |
| SCHEMBL390081 | 0.72 | GPR119 (0.60) | GPR119CYP3A4CYP2C19CNR2SCN9A | |
| SCHEMBL15315317 | 0.70 | GPR119 (0.75) | GPR119CYP3A4CYP2C19CNR2 | |
| SCHEMBL15312685 | 0.69 | GPR119 (0.77) | GPR119CYP3A4CYP2C19CNR2SCN9A | |
| SCHEMBL12506097 | 0.69 | GPR119 (1.00) | GPR119CYP3A4CYP2C19 | |
| SCHEMBL12068300 | 0.69 | GPR119 (0.52) | GPR119CYP3A4CYP2C19CNR2SCN9A | |
| SCHEMBL12506049 | 0.69 | GPR119 (0.86) | GPR119CYP3A4CYP2C19CNR2 | |
| SCHEMBL12506086 | 0.69 | GPR119 (0.78) | GPR119CYP3A4CYP2C19CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8853213-B2 | Bicyclic compound for modulating G protein-coupled receptors | HANMI PHARM. CO., LTD (KR) | 2014-10-07 | — | — | US | disclosed |
| US-8853213-B2 | Bicyclic compound for modulating G protein-coupled receptors | HANMI PHARM. CO., LTD (KR) | 2014-10-07 | — | — | US | disclosed |