Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1614431 | 1.00 | ALOX15 (0.58) | ALOX15SIGMAR1KEAP1SMN1; SMN2HRH3 | |
| SCHEMBL1614410 | 1.00 | ALOX15 (0.58) | ALOX15SIGMAR1KEAP1SMN1; SMN2HRH3 | |
| SCHEMBL1615270 | 1.00 | ALOX15 (0.58) | ALOX15SIGMAR1KEAP1SMN1; SMN2HRH3 | |
| SCHEMBL1614358 | 1.00 | ALOX15 (0.58) | ALOX15SIGMAR1KEAP1SMN1; SMN2HRH3 | |
| SCHEMBL1615521 | 1.00 | ALOX15 (0.58) | ALOX15SIGMAR1KEAP1SMN1; SMN2HRH3 | |
| SCHEMBL1615517 | 0.97 | ALOX15 (0.61) | ALOX15SIGMAR1KEAP1SMN1; SMN2HRH3 | |
| SCHEMBL4666999 | 0.97 | — | — | |
| SCHEMBL18071938 | 0.94 | KEAP1 (0.61) | ALOX15SIGMAR1KEAP1SMN1; SMN2ACE2 | |
| SCHEMBL9587121 | 0.94 | KEAP1 (0.61) | ALOX15SIGMAR1KEAP1SMN1; SMN2ACE2 | |
| SCHEMBL9801124 | 0.92 | ALOX15 (0.72) | ALOX15SIGMAR1KEAP1SMN1; SMN2ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338065-B2 | Electrophotographic photoreceptor and image forming apparatus provided with the same | SHARP KABUSHIKI KAISHA (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20110085823-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS PROVIDED WITH THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2011-04-14 | — | — | US | disclosed |
| EP-2139461-A2 | AMINO DERIVATIVES TO PREVENT NEPHROTOXICITY AND CANCER | Recepticon Aps (DK) | 2010-01-06 | — | — | EP | disclosed |
| WO-2008113364-A2 | AMINO DERIVATIVES TO PREVENT NEPHROTOXICITY AND CANCER | RECEPTICON APS (DK) | 2008-09-25 | — | — | WO | disclosed |