Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | LAP3 | P28838 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | UBE2N | P61088 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28300172 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL28298671 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL1614433 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL1614413 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL1614359 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL28298745 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL1615271 | 0.98 | OPRM1 (0.46) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL28298726 | 0.96 | OPRM1 (0.44) | OPRM1SPHK1TP53LAP3CYP2D6 | |
| SCHEMBL1615523 | 0.93 | OPRM1 (0.39) | OPRM1SPHK1TP53CYP2D6SLC1A2 | |
| SCHEMBL9417420 | 0.91 | OPRM1 (0.44) | OPRM1SPHK1TP53LAP3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338065-B2 | Electrophotographic photoreceptor and image forming apparatus provided with the same | SHARP KABUSHIKI KAISHA (JP) | 2012-12-25 | — | — | US | disclosed |
| US-20110085823-A1 | ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND IMAGE FORMING APPARATUS PROVIDED WITH THE SAME | SHARP KABUSHIKI KAISHA (JP) | 2011-04-14 | — | — | US | disclosed |