Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28755858 | 0.86 | GRIK1 (0.36) | GRIK1ALDH1A1TRPA1LMNANPSR1 | |
| SCHEMBL16881890 | 0.81 | GRIK1 (0.43) | GRIK1MAPT | |
| SCHEMBL5963393 | 0.81 | ALDH1A1 (0.46) | GRIK1ALDH1A1TRPA1LMNANPSR1 | |
| SCHEMBL5963394 | 0.81 | ALDH1A1 (0.46) | GRIK1ALDH1A1TRPA1LMNANPSR1 | |
| SCHEMBL4661706 | 0.81 | GAA (0.47) | GRIK1ALDH1A1TRPA1LMNANPSR1 | |
| SCHEMBL28582961 | 0.79 | CYP2D6 (0.45) | GRIK1ALDH1A1TRPA1LMNANPSR1 | |
| SCHEMBL2226451 | 0.79 | GRIK1 (0.39) | GRIK1ALDH1A1LMNANPSR1MEN1 | |
| SCHEMBL5963131 | 0.78 | NPSR1 (0.38) | GRIK1ALDH1A1TRPA1LMNANPSR1 | |
| SCHEMBL28072 | 0.78 | NPSR1 (0.38) | GRIK1ALDH1A1TRPA1LMNANPSR1 | |
| SCHEMBL5963310 | 0.78 | ALDH1A1 (0.43) | GRIK1ALDH1A1TRPA1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9073885-B2 | Vitamin D3 lactone derivatives | TEIJIN PHARMA LIMITED (JP) | 2015-07-07 | — | — | US | disclosed |
| US-9073885-B2 | Vitamin D3 lactone derivatives | TEIJIN PHARMA LIMITED (JP) | 2015-07-07 | — | — | US | disclosed |
| EP-1589009-B1 | VITAMIN D3 LACTONE DERIVATIVE | TEIJIN PHARMA LTD (JP) | 2014-10-08 | — | — | EP | disclosed |