Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | KYAT1 | Q16773 | 5/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28755858 | 0.83 | GRIK1 (0.36) | GRIK1ALDH1A1CYP2D6SMN1; SMN2NPSR1 | |
| SCHEMBL16152829 | 0.79 | GRIK1 (0.41) | GRIK1ALDH1A1CYP2D6SMN1; SMN2NPSR1 | |
| SCHEMBL3927257 | 0.78 | GRIK1 (0.55) | GRIK1CYP2D6EGLN1GABRPGABRD | |
| SCHEMBL4661706 | 0.78 | GAA (0.47) | GRIK1ALDH1A1CYP2D6SMN1; SMN2EGLN1 | |
| SCHEMBL11398954 | 0.75 | NPSR1 (0.42) | ALDH1A1CYP2D6SMN1; SMN2EGLN1KYAT1 | |
| SCHEMBL1408810 | 0.74 | NPSR1 (0.50) | ALDH1A1CYP2D6SMN1; SMN2NPSR1GLO1 | |
| SCHEMBL5085513 | 0.74 | NPSR1 (0.46) | GRIK1ALDH1A1CYP2D6SMN1; SMN2EGLN1 | |
| SCHEMBL5085510 | 0.74 | NPSR1 (0.46) | GRIK1ALDH1A1CYP2D6SMN1; SMN2EGLN1 | |
| SCHEMBL28582961 | 0.73 | CYP2D6 (0.45) | GRIK1ALDH1A1CYP2D6SMN1; SMN2EGLN1 | |
| SCHEMBL12553979 | 0.72 | NPSR1 (0.38) | GRIK1ALDH1A1CYP2D6SMN1; SMN2EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110256229-A | A method of preparing 3- isobutylglutaric acid | 常州工程职业技术学院 | 2019-09-20 | — | — | CN | claimed |
| CN-115536524-B | Preparation method of 3-isobutyl glutaric acid | 常州大学 | 2024-05-28 | — | — | CN | disclosed |
| CN-115536524-A | Preparation method of 3-isobutyl glutaric acid | 常州大学 | 2022-12-30 | — | — | CN | disclosed |
| CN-111333529-A | Preparation method of pregabalin | 北京万全德众医药生物技术有限公司 | 2020-06-26 | — | — | CN | disclosed |
| CN-110256229-A | A method of preparing 3- isobutylglutaric acid | 常州工程职业技术学院 | 2019-09-20 | — | — | CN | disclosed |
| WO-2011141923-A2 | IMPROVED SYNTHESIS OF OPTICALLY PURE (S) - 3-CYANO-5-METHYL-HEXANOIC ACID ALKYL ESTER, AN INTERMEDIATE OF (S)- PREGABALIN | LUPIN LIMITED (IN) | 2011-11-17 | — | — | WO | disclosed |
| WO-2011086565-A1 | METHOD FOR PREPARATION OF ENANTIOMERICALLY ENRICHED AND/OR RACEMIC GAMMA-AMINO ACIDS | LUPIN LIMITED (IN) | 2011-07-21 | — | — | WO | disclosed |
| WO-2010061403-A2 | PROCESS TO PREPARE HIGHLY PURE (S)-PREGABALIN | IND-SWIFT LABORATORIES LIMITED (IN) | 2010-06-03 | — | — | WO | disclosed |
| WO-2009044409-A2 | NOVEL RESOLUTION PROCESS FOR PREGABALIN | NATCO PHARMA LIMITED (IN) | 2009-04-09 | — | — | WO | disclosed |
| EP-0830338-B1 | Method of making 3-(aminomethyl)-5-methylhexanoic acid | WARNER LAMBERT CO (US) | 2001-12-12 | — | — | EP | disclosed |
| US-20010016665-A1 | METHOD OF MAKING (S)-3-(AMINOMETHYL) -5- METHYLHEXANOIC ACID | GROTE TODD MICHEL (US) | 2001-08-23 | — | — | US | disclosed |
| US-6046353-A | Method of making (S)-3-(aminomethyl)-5-methylhexanoic acid | WARNER-LAMBERT COMPANY (US) | 2000-04-04 | — | — | US | disclosed |
| US-5840956-A | Method of making (S)-3-(Aminomethyl)-5-Methylhexanoic acid | WARNER-LAMBERT COMPANY (US) | 1998-11-24 | — | — | US | disclosed |
| EP-0830338-A1 | METHOD OF MAKING (S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID | WARNER-LAMBERT COMPANY (US) | 1998-03-25 | — | — | EP | disclosed |
| US-5637767-A | Method of making (S)-3-(aminomethyl)-5-methylhexanoic acid | WARNER-LAMBERT COMPANY (US) | 1997-06-10 | — | — | US | disclosed |
| WO-1996040617-A1 | METHOD OF MAKING (S)-3-(AMINOMETHYL)-5-METHYLHEXANOIC ACID | WARNER-LAMBERT COMPANY (US) | 1996-12-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010016665-A1 | METHOD OF MAKING (S)-3-(AMINOMETHYL) -5- METHYLHEXANOIC ACID | APEH, CA6, ALKBH3 | GRIK1 964/4885ALDH1A1 316/4885CYP2D6 775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.