SCHEMBL161540

SCHEMBL161540

O=C=Nc1ccc(F)c(F)c1

nearest known ligand 0.52

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.52
TDP1 Q9NUW8 1/20 0.52
CYP3A4 P08684 3/20 0.48
TRPA1 O75762 1/20 0.48
TSHR P16473 1/20 0.45
CYP1A2 P05177 1/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
LMNA P02545 1/20 0.32
TP53 P04637 1/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
HSD17B10 Q99714 1/20 0.32
IDO1 P14902 1/20 0.32
GRM5 P41594 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29824353 1.00 MAPK1 (0.52) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL6418213 0.86 CYP3A4 (0.46) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL7158060 0.83 CYP3A4 (0.60) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL9630076 0.83 CYP3A4 (0.55) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL29454784 0.81 MAPK1 (0.68) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL418944 0.81 CYP3A4 (0.58) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL15620862 0.81 MAPK1 (0.47) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL9859656 0.81 MAPK1 (0.47) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL3831454 0.81 MAPK1 (0.68) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL29648923 0.81 CYP3A4 (0.58) MAPK1TDP1CYP3A4TRPA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 522 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912405-A Fluothidiazuron derivative and preparation method thereof 河南省科学院高新技术研究中心 2025-05-02 CN claimed
CN-118638407-A Modified nylon material for laser welding and preparation method thereof 瑞安市君诚塑胶制造有限公司 2024-09-13 CN claimed
CN-115746696-B Polyimide paint for high-heat-resistance enameled wire and high-heat-resistance enameled wire 浙江中科玖源新材料有限公司 2023-12-19 CN claimed
CN-115746696-A Polyimide paint for high-heat-resistance enameled wire and high-heat-resistance enameled wire 浙江中科玖源新材料有限公司 2023-03-07 CN claimed
EP-1377589-B1 OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS PHARMACIA ITALIA SPA (IT) 2005-09-07 EP claimed
CN-122025811-A High-temperature electrolyte additive, electrolyte and lithium ion battery 西安热工研究院有限公司 2026-05-12 CN disclosed
EP-4713378-A1 ESTERIFIED ETHANOLAMINES FOR PREPARING ISOCYANURATE POLYMERS Covestro Deutschland AG (DE) 2026-03-25 EP disclosed
US-12479850-B2 Compound having Axl and c-Met kinase inhibitory activity, preparation thereof and application thereof SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2025-11-25 US disclosed
CN-119912405-A Fluothidiazuron derivative and preparation method thereof 河南省科学院高新技术研究中心 2025-05-02 CN disclosed
CN-119908364-A Cotton defoliant containing fluhiuron derivative and application thereof 河南省科学院高新技术研究中心 2025-05-02 CN disclosed
US-20250074901-A1 NOVEL HETEROARYL COMPOUNDS ANGELINI PHARMA S.P.A. (IT) 2025-03-06 US disclosed
EP-3774961-B1 ADDUCTS OF AMINE CATALYSTS FOR PRODUCING ISOCYANURATE POLYMERS COVESTRO DEUTSCHLAND AG (DE) 2025-01-15 EP disclosed
US-4996208-A Pesticidal thiazolopyrimidine derivatives BAYER AKTIENGESELLSCHAFT (DE) 1991-02-26 US disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
EP-0340243-A1 CC-1065 ANALOGS. UPJOHN CO (US) 1989-11-08 EP disclosed
EP-0324175-A1 Difluorphenyl urea derivatives BAYER AG (DE) 1989-07-19 EP disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
WO-1988004659-A2 NOVEL CC-1065 ANALOGS THE UPJOHN COMPANY (US) 1988-06-30 WO disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed
US-4131751-A PHENYLENE, PLANT GROWTH REGULATORS BASF AKTIENGESELLSCHAFT (DE) 1978-12-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250074901-A1 NOVEL HETEROARYL COMPOUNDS H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CYP3A43, F12 MAPK1 2595/4885TDP1 2961/4885CYP3A4 18/4885
US-12479850-B2 Compound having Axl and c-Met kinase inhibitory activity, preparation thereof and application thereof MET, MERTK, AXL MAPK1 121/4885TDP1 4589/4885CYP3A4 3564/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.