SCHEMBL16154841

SCHEMBL16154841

CCCCC/C=C\C/C=C\CCCCCCCCOc1cc(CN2C(=O)c3ccccc3C2=O)cc(OCCCCCCCC/C=C\C/C=C\CCCCC)c1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 2/20 0.42
MAPT P10636 1/20 0.40
RAB9A P51151 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
FAAH O00519 3/20 0.40
EPHX2 P34913 1/20 0.40
HPGD P15428 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH1A1 P00352 1/20 0.40
RECQL P46063 1/20 0.40
MGLL Q99685 2/20 0.40
KMT2A Q03164 1/20 0.39
CASP3 P42574 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
PTPN11 Q06124 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17685738 1.00 PPARA (0.42) PPARAMAPTRAB9ASMN1; SMN2FAAH
SCHEMBL30037084 0.91 RAB9A (0.48) MAPTRAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL30035872 0.91 RAB9A (0.48) MAPTRAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL30036373 0.91 RAB9A (0.48) MAPTRAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL31006993 0.91 RAB9A (0.48) MAPTRAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL30036068 0.91 RAB9A (0.48) MAPTRAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL30037069 0.91 RAB9A (0.48) MAPTRAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL30035606 0.91 RAB9A (0.48) MAPTRAB9ASMN1; SMN2HPGDALDH1A1
SCHEMBL15923238 0.81 KMT2A (0.52) MAPTRAB9ASMN1; SMN2HPGDKDM4E
SCHEMBL15923064 0.81 KMT2A (0.52) MAPTRAB9ASMN1; SMN2HPGDKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3608308-B1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2021-07-21 EP disclosed
EP-3608308-B1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2021-07-21 EP disclosed
CN-107879960-B Lipids and lipid compositions for delivery of active ingredients 诺华股份有限公司 2021-06-22 CN disclosed
US-10792361-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2020-10-06 US disclosed
US-10792361-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2020-10-06 US disclosed
US-10729775-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2020-08-04 US disclosed
EP-3608308-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS Novartis AG (CH) 2020-02-12 EP disclosed
EP-2964608-B1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2019-08-28 EP disclosed
EP-2964608-B1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2019-08-28 EP disclosed
US-20180369386-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. 2018-12-27 US disclosed
US-10124065-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2018-11-13 US disclosed
US-20170196979-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2017-07-13 US disclosed
US-20170196979-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2017-07-13 US disclosed
US-9504747-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2016-11-29 US disclosed
US-9504747-B2 Lipids and lipid compositions for the delivery of active agents NOVARTIS AG (CH) 2016-11-29 US disclosed
US-20160106842-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. 2016-04-21 US disclosed
US-20160106842-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. 2016-04-21 US disclosed
US-20160106842-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC. 2016-04-21 US disclosed
US-20140303232-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2014-10-09 US disclosed
US-20140303232-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS NOVARTIS AG (CH) 2014-10-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10124065-B2 Lipids and lipid compositions for the delivery of active agents LIPA, LPAR1, LPAR4 PPARA 1199/4885MAPT 4044/4885RAB9A 553/4885
US-20180369386-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, LPAR1, LPAR4 PPARA 1199/4885MAPT 4044/4885RAB9A 553/4885
US-20160106842-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, LPAR1, LPAR4 PPARA 1199/4885MAPT 4044/4885RAB9A 553/4885
US-10792361-B2 Lipids and lipid compositions for the delivery of active agents LIPA, LPAR1, LPAR4 PPARA 1199/4885MAPT 4044/4885RAB9A 553/4885
US-20140303232-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, LPAR1, LPAR4 PPARA 1199/4885MAPT 4044/4885RAB9A 553/4885
US-10729775-B2 Lipids and lipid compositions for the delivery of active agents LIPA, LPAR1, LPAR4 PPARA 1199/4885MAPT 4044/4885RAB9A 553/4885
US-20170196979-A1 LIPIDS AND LIPID COMPOSITIONS FOR THE DELIVERY OF ACTIVE AGENTS LIPA, LPAR1, LPAR4 PPARA 1199/4885MAPT 4044/4885RAB9A 553/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.