SCHEMBL31006993

SCHEMBL31006993

CCCCCCCCCCCCCCOc1cc(CN2C(=O)c3ccccc3C2=O)cc(OCCCCCCCCCCC)c1

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.48
MAPT P10636 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
CASP3 P42574 1/20 0.46
HPGD P15428 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
KMT2A Q03164 2/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
PTPN11 Q06124 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
ALDH1A1 P00352 1/20 0.45
PLA2G2A P14555 1/20 0.44
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30037069 1.00 RAB9A (0.48) RAB9AMAPTSMN1; SMN2CASP3HPGD
SCHEMBL30035606 1.00 RAB9A (0.48) RAB9AMAPTSMN1; SMN2CASP3HPGD
SCHEMBL30036068 1.00 RAB9A (0.48) RAB9AMAPTSMN1; SMN2CASP3HPGD
SCHEMBL30035872 1.00 RAB9A (0.48) RAB9AMAPTSMN1; SMN2CASP3HPGD
SCHEMBL30037084 1.00 RAB9A (0.48) RAB9AMAPTSMN1; SMN2CASP3HPGD
SCHEMBL30036373 1.00 RAB9A (0.48) RAB9AMAPTSMN1; SMN2CASP3HPGD
SCHEMBL16154841 0.91 PPARA (0.42) RAB9AMAPTSMN1; SMN2CASP3HPGD
SCHEMBL17685738 0.91 PPARA (0.42) RAB9AMAPTSMN1; SMN2CASP3HPGD
SCHEMBL15923064 0.90 KMT2A (0.52) RAB9AMAPTSMN1; SMN2HPGDKMT2A
SCHEMBL15923238 0.90 KMT2A (0.52) RAB9AMAPTSMN1; SMN2HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119233964-A Single component delivery system for nucleic acids 宾夕法尼亚大学理事会 2024-12-31 CN disclosed
US-20240252677-A1 ONE-COMPONENT DELIVERY SYSTEM FOR NUCLEIC ACIDS THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2024-08-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240252677-A1 ONE-COMPONENT DELIVERY SYSTEM FOR NUCLEIC ACIDS TLR3, TLR9, ADAR RAB9A 4225/4885MAPT 3202/4885SMN1; SMN2 472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.