Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 13/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 13/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 13/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 13/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 13/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 13/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 13/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 13/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 13/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 13/20 | 0.53 |
| ▸ | UCHL5 | Q9Y5K5 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.48 |
| ▸ | TEK | Q02763 | 2/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16155169 | 0.97 | HDAC3 (0.54) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16155361 | 0.95 | HDAC3 (0.56) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16238536 | 0.93 | UCHL5 (0.52) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16155383 | 0.81 | UCHL5 (0.49) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16068165 | 0.79 | TEK (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL460447 | 0.79 | TEK (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16775813 | 0.77 | UCHL5 (0.44) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16155382 | 0.77 | UCHL5 (0.46) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL16155170 | 0.77 | NAMPT (0.45) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL14987759 | 0.76 | TEK (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014165792-A2 | MACROLIDES AND METHODS OF THEIR PREPARATION AND USE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-10-09 | — | — | WO | disclosed |