Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13721165 | 0.91 | KMT2A (0.48) | AKR1B1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13721316 | 0.87 | KDM4E (0.45) | AKR1B1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13721379 | 0.87 | MEN1 (0.46) | ALDH1A1MEN1KMT2ALMNAL3MBTL1 | |
| SCHEMBL13720819 | 0.86 | KDM4E (0.45) | AKR1B1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13858401 | 0.85 | KDM4E (0.45) | AKR1B1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13720757 | 0.84 | KDM4E (0.41) | AKR1B1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL16155987 | 0.81 | PRMT1 (0.46) | AKR1B1ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL13721378 | 0.80 | HPGD (0.47) | AKR1B1ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL13720425 | 0.79 | MAPK8 (0.41) | ALDH1A1MEN1KMT2ALMNAHPGD | |
| SCHEMBL13721003 | 0.78 | KDM4E (0.49) | AKR1B1ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859549-B2 | Potassium channel modulators | ABBVIE, INC. (US) | 2014-10-14 | — | — | US | claimed |
| US-8859549-B2 | Potassium channel modulators | ABBVIE, INC. (US) | 2014-10-14 | — | — | US | disclosed |