Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGFRL1 | Q5TC84 | 5/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16156007 | 1.00 | OGFRL1 (0.42) | OGFRL1OPRM1OPRK1OPRD1CNR2 | |
| SCHEMBL13721202 | 0.83 | OGFRL1 (0.39) | OGFRL1OPRM1OPRK1OPRD1CNR2 | |
| SCHEMBL13721204 | 0.83 | OGFRL1 (0.39) | OGFRL1OPRM1OPRK1OPRD1CNR2 | |
| SCHEMBL1787044 | 0.81 | RAB9A (0.45) | CNR2CNR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL30796416 | 0.81 | RAB9A (0.45) | CNR2CNR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL1787041 | 0.81 | RAB9A (0.45) | CNR2CNR1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13858557 | 0.80 | HPGD (0.44) | SMN1; SMN2ALDH1A1LMNATSHRHTT | |
| SCHEMBL1788439 | 0.79 | MEN1 (0.44) | ALDH1A1LMNA | |
| SCHEMBL1788438 | 0.79 | MEN1 (0.44) | ALDH1A1LMNA | |
| SCHEMBL30796361 | 0.79 | MEN1 (0.44) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859549-B2 | Potassium channel modulators | ABBVIE, INC. (US) | 2014-10-14 | — | — | US | claimed |
| US-8859549-B2 | Potassium channel modulators | ABBVIE, INC. (US) | 2014-10-14 | — | — | US | disclosed |