Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1787041 | 1.00 | RAB9A (0.45) | RAB9AALDH1A1CNR2ATMKMT2A | |
| SCHEMBL30796416 | 1.00 | RAB9A (0.45) | RAB9AALDH1A1CNR2ATMKMT2A | |
| SCHEMBL1788438 | 0.92 | MEN1 (0.44) | ALDH1A1KMT2AMEN1TP53NPSR1 | |
| SCHEMBL30796361 | 0.92 | MEN1 (0.44) | ALDH1A1KMT2AMEN1TP53NPSR1 | |
| SCHEMBL1788439 | 0.92 | MEN1 (0.44) | ALDH1A1KMT2AMEN1TP53NPSR1 | |
| SCHEMBL16156007 | 0.81 | OGFRL1 (0.42) | ALDH1A1CNR2CNR1SMN1; SMN2 | |
| SCHEMBL16156008 | 0.81 | OGFRL1 (0.42) | ALDH1A1CNR2CNR1SMN1; SMN2 | |
| SCHEMBL1791109 | 0.81 | ADORA3 (0.41) | ALDH1A1CNR2KMT2AMEN1CNR1 | |
| SCHEMBL1791112 | 0.81 | ADORA3 (0.41) | ALDH1A1CNR2KMT2AMEN1CNR1 | |
| SCHEMBL1788965 | 0.77 | RAB9A (0.48) | RAB9AALDH1A1ATMKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629143-B2 | Potassium channel modulators | ABBVIE INC. (US) | 2014-01-14 | — | — | US | claimed |
| US-20110124642-A1 | POTASSIUM CHANNEL MODULATORS | ABBOTT LABORATORIES (US) | 2011-05-26 | — | — | US | claimed |
| US-8629143-B2 | Potassium channel modulators | ABBVIE INC. (US) | 2014-01-14 | — | — | US | disclosed |
| US-20110124642-A1 | POTASSIUM CHANNEL MODULATORS | ABBOTT LABORATORIES (US) | 2011-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110124642-A1 | POTASSIUM CHANNEL MODULATORS | KCNQ1, KCNQ2, KCNQ3 | RAB9A 1521/4885ALDH1A1 1644/4885CNR2 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.