SCHEMBL16158335

SCHEMBL16158335

c1ccc(-c2ccc(-c3ccc(N(c4ccc(-c5ccc6c(c5)c5ccccc5n6-c5ccc6ccccc6c5)cc4)c4ccc5c6ccccc6c6ccccc6c5c4)cc3)cc2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSPO P30536 4/20 0.38
KDM4E B2RXH2 1/20 0.35
ATM Q13315 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
RAC2 P15153 1/20 0.33
RAC3 P60763 1/20 0.33
CDC42 P60953 1/20 0.33
RAC1 P63000 1/20 0.33
NPY5R Q15761 1/20 0.32
HDAC4 P56524 1/20 0.32
HPGD P15428 1/20 0.31
PTGER4 P35408 1/20 0.31
PTGES O14684 1/20 0.31
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31
TUBA1B P68363 1/20 0.31
TUBA4A P68366 1/20 0.31
TUBB4B P68371 1/20 0.31
TUBB3 Q13509 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16158273 0.97 TSPO (0.36) TSPOKDM4EATML3MBTL1RAC2
SCHEMBL24221812 0.94 L3MBTL1 (0.42) TSPOKDM4EATML3MBTL1RAC2
SCHEMBL16158372 0.94 TSPO (0.40) TSPOKDM4EATML3MBTL1RAC2
SCHEMBL24221716 0.94 TSPO (0.40) TSPOKDM4EATML3MBTL1RAC2
SCHEMBL16158301 0.94 TSPO (0.42) TSPOKDM4EATML3MBTL1RAC2
SCHEMBL13803263 0.94 TSPO (0.42) TSPOKDM4EATML3MBTL1RAC2
SCHEMBL17931561 0.94 KDM4E (0.39) TSPOKDM4EATML3MBTL1RAC2
SCHEMBL26340239 0.94 TSPO (0.36) TSPOKDM4EATML3MBTL1RAC2
SCHEMBL14728173 0.93 KDM4E (0.35) TSPOKDM4EATML3MBTL1RAC2
SCHEMBL14849224 0.93 TSPO (0.36) TSPOKDM4EATML3MBTL1RAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014163228-A1 NOVEL ORGANIC ELECTROLUMINESCENT ELEMENT COMPOUND AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME (주)피엔에이치테크 (KR) 2014-10-09 WO disclosed