Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 6/20 | 0.51 |
| ▸ | KLK5 | Q9Y337 | 5/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.49 |
| ▸ | CDC25B | P30305 | 5/20 | 0.49 |
| ▸ | PTPN2 | P17706 | 4/20 | 0.49 |
| ▸ | CDC25A | P30304 | 3/20 | 0.49 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16158881 | 1.00 | KLK7 (0.51) | KLK7KLK5PPARAPTPN1CDC25B | |
| SCHEMBL16144930 | 0.85 | PTPN1 (0.56) | KLK7KLK5PPARAPTPN1CDC25B | |
| SCHEMBL16144925 | 0.85 | PTPN1 (0.56) | KLK7KLK5PPARAPTPN1CDC25B | |
| SCHEMBL10314154 | 0.84 | PTPN1 (0.44) | KLK7KLK5PPARAPTPN1CDC25B | |
| SCHEMBL10314151 | 0.81 | PTPN1 (0.44) | KLK7KLK5PPARAPTPN1CDC25B | |
| SCHEMBL17447104 | 0.81 | KLK7 (0.45) | KLK7KLK5PPARAPTPN1CDC25B | |
| SCHEMBL7518373 | 0.80 | PPARA (0.74) | KLK7KLK5PPARACTSSPPARG | |
| SCHEMBL19853661 | 0.80 | PPARA (0.74) | KLK7KLK5PPARACTSSPPARG | |
| SCHEMBL10314148 | 0.76 | PTPN1 (0.48) | KLK7KLK5PPARAPTPN1CDC25B | |
| SCHEMBL8138595 | 0.76 | PPARA (0.60) | KLK7KLK5PPARACTSSPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9359394-B2 | Stereoselective glycosylation reactions | TRUSTEES OF TUFTS COLLEGE (US) | 2016-06-07 | — | — | US | disclosed |
| US-20140303359-A1 | Stereoselective Glycosylation Reactions | TRUSTEES OF TUFTS COLLEGE (US) | 2014-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303359-A1 | Stereoselective Glycosylation Reactions | UGGT1, ST6GAL1, FUT6 | KLK7 699/4885KLK5 2734/4885PPARA 3554/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.