SCHEMBL16158993

SCHEMBL16158993

C=CN(C=C)C(=O)N(C=C)C=C

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.33
FGFR4 P22455 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28937210 0.83 LMNA (0.30) LMNA
SCHEMBL28533051 0.76 ALDH1A1 (0.30) ALDH1A1
SCHEMBL5933269 0.74
SCHEMBL2872530 0.74
SCHEMBL6920377 0.72
SCHEMBL5932643 0.72
SCHEMBL368600 0.72
SCHEMBL5932655 0.72
SCHEMBL3124801 0.72
SCHEMBL3131805 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9163102-B2 Soluble branched polymers ISP INVESTMENTS INC. (US) 2015-10-20 US disclosed
US-9163102-B2 Soluble branched polymers ISP INVESTMENTS INC. (US) 2015-10-20 US disclosed
US-20140303313-A1 SOLUBLE BRANCHED POLYMERS ISP INVESTMENTS INC. (US) 2014-10-09 US disclosed
US-20140303313-A1 SOLUBLE BRANCHED POLYMERS ISP INVESTMENTS INC. (US) 2014-10-09 US disclosed