SCHEMBL16159262

SCHEMBL16159262

c1cc(-c2ccc3c(c2)C2(c4ccccc4-c4ccccc42)c2cc(-c4cccc(-c5cncs5)n4)c4ccccc4c2-3)nc(-c2cncs2)c1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
AR P10275 1/20 0.35
PLAUR Q03405 1/20 0.33
PIM1 P11309 4/20 0.32
PDK2 Q15119 4/20 0.32
IDO1 P14902 1/20 0.31
IMPDH2 P12268 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16159225 0.90 AR (0.35) ARPLAURPIM1IMPDH2
SCHEMBL16159234 0.89 PDK2 (0.38) ARPLAURPIM1PDK2IDO1
SCHEMBL16159224 0.85 AR (0.34) ARPLAURPIM1IDO1IMPDH2
SCHEMBL16159641 0.85 KDR (0.35) PLAURPIM1PDK2IDO1
SCHEMBL16159125 0.83 PDK2 (0.36) PLAURPIM1PDK2
SCHEMBL16159443 0.81 PIM1 (0.36) PLAURPIM1PDK2
SCHEMBL16159453 0.80 PDK2 (0.35) ARPDK2
SCHEMBL16159266 0.80 PDK2 (0.47) PDK2IMPDH2
SCHEMBL17116103 0.79 PDK2 (0.39) PIM1PDK2
SCHEMBL16159222 0.79 PIM1 (0.38) ARPLAURPIM1PDK2IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160118598-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME JNC CORPORATION (JP) 2016-04-28 US disclosed
US-20160118598-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME JNC CORPORATION (JP) 2016-04-28 US disclosed
WO-2014163173-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME JNC株式会社 (JP) 2014-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160118598-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME HVCN1, VDAC1, SLC26A3 AR 349/4885PLAUR 4293/4885PIM1 2642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.