SCHEMBL16159397

SCHEMBL16159397

c1ccc(-c2ccc3c4cc(-c5cccc(-c6cocn6)c5)ccc4c4ccc(-c5cccc(-c6cocn6)c5)cc4c3c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 2/20 0.54
HDAC4 P56524 1/20 0.39
KMO O15229 2/20 0.38
EGFR P00533 1/20 0.37
PLAU P00749 2/20 0.37
MAP4K4 O95819 1/20 0.36
IMPDH2 P12268 1/20 0.36
PFKFB3 Q16875 1/20 0.36
CDK8 P49336 1/20 0.35
GSK3B P49841 1/20 0.35
PLG P00747 1/20 0.35
JAK2 O60674 2/20 0.34
TRIM58 Q8NG06 1/20 0.34
PIK3CA P42336 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16159400 0.95 SCN9A (0.55) SCN9AHDAC4KMOEGFRPLAU
SCHEMBL14564377 0.90 SCN9A (0.62) SCN9AHDAC4KMOEGFRIMPDH2
SCHEMBL16159135 0.89 SCN9A (0.43) SCN9AHDAC4EGFRPLAUMAP4K4
SCHEMBL16159865 0.88 SCN9A (0.49) SCN9AHDAC4KMOEGFRPLAU
SCHEMBL16159226 0.88 SCN9A (0.49) SCN9AHDAC4KMOEGFRPLAU
SCHEMBL16159195 0.88 SCN9A (0.49) SCN9AHDAC4KMOEGFRPLAU
SCHEMBL16159201 0.88 SCN9A (0.45) SCN9AHDAC4PLAUMAP4K4IMPDH2
SCHEMBL16159134 0.87 SCN9A (0.48) SCN9AHDAC4KMOEGFRPLAU
SCHEMBL16159479 0.85 SCN9A (0.46) SCN9AHDAC4KMOEGFRPLAU
SCHEMBL16159801 0.83 SCN9A (0.44) SCN9AHDAC4KMOEGFRPLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160118598-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME JNC CORPORATION (JP) 2016-04-28 US disclosed
US-20160118598-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME JNC CORPORATION (JP) 2016-04-28 US disclosed
WO-2014163173-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME JNC株式会社 (JP) 2014-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160118598-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME HVCN1, VDAC1, SLC26A3 SCN9A 1007/4885HDAC4 1855/4885KMO 1677/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.