SCHEMBL16160478

SCHEMBL16160478

c1ccc(-c2cc(-c3ccc(-n4c5ccccc5c5c6oc7ccccc7c6ccc54)cc3)nc(-c3ccc4oc5ccccc5c4c3)n2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK2 O96017 1/20 0.34
PTPRF P10586 7/20 0.33
PTPN2 P17706 7/20 0.33
PTPN1 P18031 7/20 0.33
ALDH1A1 P00352 6/20 0.33
MEN1 O00255 5/20 0.33
KMT2A Q03164 5/20 0.33
HPGD P15428 5/20 0.33
MAPT P10636 5/20 0.33
NTSR1 P30989 1/20 0.33
TSHR P16473 2/20 0.32
POLB P06746 1/20 0.32
BRCA1 P38398 1/20 0.32
HSD17B10 Q99714 1/20 0.32
KDM4E B2RXH2 4/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
LMNA P02545 1/20 0.32
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15625590 0.98 PTPRF (0.34) CHEK2PTPRFPTPN2PTPN1ALDH1A1
SCHEMBL15625556 0.95 MAPT (0.37) ALDH1A1MEN1KMT2AHPGDMAPT
SCHEMBL18253586 0.95 MAPT (0.37) ALDH1A1MEN1KMT2AHPGDMAPT
SCHEMBL21365546 0.94 ALDH1A1 (0.35) CHEK2PTPRFPTPN2PTPN1ALDH1A1
SCHEMBL15625588 0.94 MAPT (0.36) ALDH1A1MEN1KMT2AHPGDMAPT
SCHEMBL16160473 0.94 MAPT (0.36) ALDH1A1MEN1KMT2AHPGDMAPT
SCHEMBL16272527 0.93 ALDH1A1 (0.35) ALDH1A1MEN1KMT2AHPGDMAPT
SCHEMBL18564636 0.93 MEN1 (0.33) ALDH1A1MEN1KMT2AHPGDMAPT
SCHEMBL18564618 0.92 ALOX5 (0.33) ALDH1A1MEN1KMT2AHPGDMAPT
SCHEMBL18564615 0.91 MEN1 (0.33) ALDH1A1MEN1KMT2AHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140299865-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-10-09 US disclosed
US-20140299865-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-10-09 US disclosed