Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1615442 | 0.79 | SRD5A2 (0.30) | SRD5A2 | |
| SCHEMBL9081992 | 0.75 | — | — | |
| SCHEMBL31174168 | 0.73 | — | — | |
| SCHEMBL27833958 | 0.67 | SRD5A2 (0.32) | SRD5A2 | |
| SCHEMBL28850169 | 0.67 | SRD5A2 (0.32) | SRD5A2 | |
| SCHEMBL31403431 | 0.66 | SRD5A2 (0.31) | SRD5A2 | |
| SCHEMBL27584931 | 0.66 | SRD5A2 (0.31) | SRD5A2 | |
| SCHEMBL28760436 | 0.64 | SRD5A2 (0.30) | SRD5A2 | |
| SCHEMBL27854720 | 0.64 | SRD5A2 (0.30) | SRD5A2 | |
| SCHEMBL27660605 | 0.64 | SRD5A2 (0.30) | SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9198872-B2 | Dendritic and hyperbranched polymers for cellular encapsulation and functionalization | UNIVERSITY OF MIAMI (US) | 2015-12-01 | — | — | US | disclosed |
| US-8728520-B2 | Cross-linked alginate-polyalkylene glycol polymer coatings for encapsulation and methods of making the same | UNIVERSITY OF MIAMI (US) | 2014-05-20 | — | — | US | disclosed |
| US-20120328673-A1 | DENDRITIC AND HYPERBRANCHED POLYMERS FOR CELLULAR ENCAPSULATION AND FUNCTIONALIZATION | UNIVERSITY OF MIAMI (US) | 2012-12-27 | — | — | US | disclosed |
| US-8076496-B2 | Chemoselective ligation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-12-13 | — | — | US | disclosed |
| US-20110236930-A1 | CHEMOSELECTIVE LIGATION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-09-29 | — | — | US | disclosed |
| US-7939626-B2 | Condensation of a specifically engineered phosphine containing a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine by-product and producing an amide bond in final product | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-05-10 | — | — | US | disclosed |
| US-7923582-B2 | Condensation of a specifically engineered phosphine containing a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine by-product and producing an amide bond in final product | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-04-12 | — | — | US | disclosed |
| US-7838665-B2 | Chemoselective ligation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-11-23 | — | — | US | disclosed |
| WO-2010078202-A1 | CROSS-LINKED ALGINATE-POLYALKYLENE GLYCOL POLYMER COATINGS FOR ENCAPSULATION AND METHODS OF MAKING THE SAME | UNIVERSITY OF MIAMI (US) | 2010-07-08 | — | — | WO | disclosed |
| US-20100143464-A1 | CROSS-LINKED ALGINATE-POLYALKYLENE GLYCOL POLYMER COATINGS FOR ENCAPSULATION AND METHODS OF MAKING THE SAME | UNIVERSITY OF MIAMI | 2010-06-10 | — | — | US | disclosed |
| US-7667012-B2 | Condensation of a specifically engineered phosphine containing a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine by-product and producing an amide bond in final product; N-azidogalactosamine | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-02-23 | — | — | US | disclosed |
| US-20080214801-A1 | CHEMOSELECTIVE LIGATION | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-09-04 | — | — | US | disclosed |
| US-20070037964-A1 | Condensation of a specifically engineered phosphine containing a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine by-product and producing an amide bond in final product | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-02-15 | — | — | US | disclosed |
| US-20060276658-A1 | Chemoselective ligation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2006-12-07 | — | — | US | disclosed |
| US-7122703-B2 | Chemoselective ligation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-10-17 | — | — | US | disclosed |
| EP-1263771-B1 | CHEMOSELECTIVE LIGATION BY USE OF A PHOSPHINE | UNIV CALIFORNIA (US) | 2006-06-14 | — | — | EP | disclosed |
| US-20050148032-A1 | Chemoselective ligation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2005-07-07 | — | — | US | disclosed |
| US-6570040-B2 | Condensation of specifically engineered phosphine which can provide for formation of amide bond between two reactive partners resulting in product comprising a phosphine moiety or which can be engineered to comprise a cleavable linker | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-05-27 | — | — | US | disclosed |
| US-20020016003-A1 | Chemoselective ligation | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2002-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120328673-A1 | DENDRITIC AND HYPERBRANCHED POLYMERS FOR CELLULAR ENCAPSULATION AND FUNCTIONALIZATION | TLR9, CD44, ITGAL | SRD5A2 4864/4885 |
| US-20020016003-A1 | Chemoselective ligation | PTMS, QPCT, DNPEP | SRD5A2 4614/4885 |
| US-20060276658-A1 | Chemoselective ligation | PTMS, PGF, ACSL3 | SRD5A2 4676/4885 |
| US-20100143464-A1 | CROSS-LINKED ALGINATE-POLYALKYLENE GLYCOL POLYMER COATINGS FOR ENCAPSULATION AND METHODS OF MAKING THE SAME | ALG1, PAG1, GALR3 | SRD5A2 3545/4885 |
| US-20110236930-A1 | CHEMOSELECTIVE LIGATION | PTMS, QPCT, DNPEP | SRD5A2 4614/4885 |
| US-20070037964-A1 | Condensation of a specifically engineered phosphine containing a cleavable linker so that a substituent of the phosphine is transferred to the azide, releasing an oxidized phosphine by-product and producing an amide bond in final product | PTMS, PHOSPHO1, QPCT | SRD5A2 4496/4885 |
| US-20080214801-A1 | CHEMOSELECTIVE LIGATION | PTMS, QPCT, DNPEP | SRD5A2 4614/4885 |
| US-20050148032-A1 | Chemoselective ligation | PTMS, QPCT, DNPEP | SRD5A2 4614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.