Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 1/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2242607 | 0.80 | GBA1 (0.40) | KDM4EGAALMNAALOX15TSHR | |
| SCHEMBL1616346 | 0.79 | MEN1 (0.46) | GLO1KDM4EGAAKMT2ALMNA | |
| SCHEMBL3844986 | 0.79 | PDPK1 (0.47) | — | |
| SCHEMBL1615546 | 0.79 | SCN1A (0.41) | KDM4EGAAKMT2ALMNAALOX15 | |
| SCHEMBL1616265 | 0.79 | SCN1A (0.41) | KDM4EGAALMNAALOX15TSHR | |
| SCHEMBL2926162 | 0.79 | SCN1A (0.41) | KDM4EGAAKMT2ALMNAALOX15 | |
| SCHEMBL2919481 | 0.79 | SCN1A (0.41) | KDM4EGAALMNAALOX15TSHR | |
| SCHEMBL1615434 | 0.77 | NFKBIA (0.42) | L3MBTL1KMT2ALMNAALOX15SMN1; SMN2 | |
| SCHEMBL1616159 | 0.75 | PRKCQ (0.39) | KDM4EGAAKMT2ALMNAALOX15 | |
| SCHEMBL1616691 | 0.75 | PFKFB3 (0.39) | KDM4ELMNAALOX15TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7923561-B2 | Quinolines | HOFFMANN-LA ROCHE INC. (US) | 2011-04-12 | — | — | US | claimed |
| US-7923561-B2 | Quinolines | HOFFMANN-LA ROCHE INC. (US) | 2011-04-12 | — | — | US | disclosed |