Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 20/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14959459 | 0.92 | TAS2R8 (0.82) | TAS2R8 | |
| SCHEMBL1279752 | 0.90 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL18351080 | 0.88 | TAS2R8 (0.76) | TAS2R8 | |
| SCHEMBL1279520 | 0.86 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1278874 | 0.86 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1616765 | 0.85 | TAS2R8 (0.86) | TAS2R8 | |
| SCHEMBL1615607 | 0.85 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL1615616 | 0.85 | TAS2R8 (1.00) | TAS2R8 | |
| SCHEMBL17480042 | 0.85 | TAS2R8 (0.85) | TAS2R8 | |
| SCHEMBL1279891 | 0.85 | TAS2R8 (1.00) | TAS2R8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8445692-B2 | Compounds that inhibit (block) bitter taste in composition and use thereof | SENOMYX INC. (US) | 2013-05-21 | — | — | US | disclosed |
| US-20120088796-A1 | COMPOUNDS THAT INHIBIT (BLOCK) BITTER TASTE IN COMPOSITION AND USE THEREOF | SENOMYX, INC. (US) | 2012-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120088796-A1 | COMPOUNDS THAT INHIBIT (BLOCK) BITTER TASTE IN COMPOSITION AND USE THEREOF | TAS2R50, TAS2R5, TAS2R1 | TAS2R8 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.