Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | POLQ | O75417 | 1/20 | 0.53 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25629360 | 0.83 | NOTUM (0.58) | NOTUMPOLQTRPV1PYGLGAA | |
| SCHEMBL6164413 | 0.83 | NOTUM (0.58) | NOTUMPOLQTRPV1PYGLGAA | |
| SCHEMBL25733507 | 0.81 | NOTUM (0.56) | NOTUMPOLQTRPV1PYGLGAA | |
| SCHEMBL3576501 | 0.81 | NOTUM (0.51) | NOTUMPOLQTRPV1PYGLGAA | |
| SCHEMBL2435091 | 0.81 | NOTUM (0.56) | NOTUMPOLQTRPV1PYGLHPGD | |
| SCHEMBL27657777 | 0.80 | NOTUM (0.59) | NOTUMPOLQTRPV1PYGLGAA | |
| SCHEMBL13824325 | 0.80 | POLQ (0.49) | POLQHTTALDH1A1MAPTGFER | |
| Hydrochloric Acid SCHEMBL5349528 | 0.80 | NOTUM (0.50) | NOTUMPOLQTRPV1PYGLGAA | |
| SCHEMBL16353843 | 0.79 | NOTUM (0.54) | NOTUMPOLQTRPV1PYGLHTT | |
| SCHEMBL6659655 | 0.79 | KMT2A (0.53) | POLQHTTALDH1A1NPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9751862-B2 | Pesticidally active substituted pyridyl carboxamides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-05 | — | — | US | disclosed |
| US-9750253-B2 | Pesticidally active substituted pyridyl carboxamides | SYNGENTA PARTICIPATIONS AG (CH) | 2017-09-05 | — | — | US | disclosed |
| US-20170107200-A1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-04-20 | — | — | US | disclosed |
| EP-2984083-B1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2017-01-25 | — | — | EP | disclosed |
| EP-3119758-A1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | Syngenta Participations AG (CH) | 2017-01-25 | — | — | EP | disclosed |
| US-20160050924-A1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2016-02-25 | — | — | US | disclosed |
| EP-2984083-A1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | Syngenta Participations AG (CH) | 2016-02-17 | — | — | EP | disclosed |
| WO-2015140222-A1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2015-09-24 | — | — | WO | disclosed |
| WO-2014166795-A1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2014-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160050924-A1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | CBR3, CBR1, CYCS | NOTUM 635/4885POLQ 2529/4885TRPV1 1532/4885 |
| US-20170107200-A1 | PESTICIDALLY ACTIVE SUBSTITUTED PYRIDYL CARBOXAMIDES | CBR3, CBR1, CYCS | NOTUM 392/4885POLQ 3696/4885TRPV1 2459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.