Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.53 |
| ▸ | POLQ | O75417 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2435091 | 0.87 | NOTUM (0.56) | NOTUMTRPV1POLQHTTPYGL | |
| SCHEMBL6164413 | 0.86 | NOTUM (0.58) | NOTUMTRPV1POLQHTTPYGL | |
| SCHEMBL16166142 | 0.83 | NOTUM (0.56) | NOTUMTRPV1POLQHTTPYGL | |
| SCHEMBL16353843 | 0.82 | NOTUM (0.54) | NOTUMTRPV1POLQHTTPYGL | |
| SCHEMBL27921411 | 0.82 | NOTUM (0.58) | NOTUMTRPV1POLQHTTPYGL | |
| SCHEMBL666963 | 0.81 | HTT (0.57) | NOTUMTRPV1HTTKCNN4KCNA5 | |
| SCHEMBL3884249 | 0.81 | NOTUM (0.56) | NOTUMTRPV1POLQHTTCHRNB2 | |
| SCHEMBL25733507 | 0.81 | NOTUM (0.56) | NOTUMTRPV1POLQHTTPYGL | |
| SCHEMBL965251 | 0.80 | NOTUM (0.51) | NOTUMTRPV1POLQHTTKCNN4 | |
| SCHEMBL3576501 | 0.80 | NOTUM (0.51) | NOTUMTRPV1POLQHTTPYGL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023098825-A1 | SOS1 INHIBITOR, PHARMACEUTICAL COMPOSITION COMPRISING SAME, AND USE THEREOF | 勤浩医药（苏州）有限公司 | 2023-06-08 | — | — | WO | disclosed |