Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16166372 | 0.80 | ADRB2 (0.41) | — | |
| SCHEMBL16166590 | 0.80 | ADRB2 (0.41) | — | |
| SCHEMBL25064763 | 0.80 | — | — | |
| SCHEMBL29693600 | 0.72 | CYP19A1 (0.42) | PDE2APDE9A | |
| SCHEMBL16166195 | 0.70 | PDE2A (0.42) | PDE2APDE9A | |
| SCHEMBL18282858 | 0.69 | PDE2A (0.49) | PDE2APDE9A | |
| SCHEMBL25008226 | 0.69 | HTR2A (0.42) | PDE9A | |
| SCHEMBL5906272 | 0.69 | PDE2A (0.49) | PDE2APDE9A | |
| SCHEMBL29693622 | 0.68 | PTPN2 (0.46) | PDE2APDE9A | |
| SCHEMBL2980379 | 0.67 | PDE2A (0.53) | PDE2APDE9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014167528-A1 | SPIROPYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF FOR THE TREATMENT OF VIRAL INFECTIONS | NOVARTIS AG (CH) | 2014-10-16 | — | — | WO | disclosed |
| WO-2014167528-A1 | SPIROPYRAZOLOPYRIDINE DERIVATIVES AND USES THEREOF FOR THE TREATMENT OF VIRAL INFECTIONS | NOVARTIS AG (CH) | 2014-10-16 | — | — | WO | disclosed |