Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23137391 | 0.94 | ACHE (0.51) | ACHEEPHX1EPHX2 | |
| SCHEMBL30354527 | 0.92 | ACHE (0.60) | ACHEEPHX1EPHX2 | |
| SCHEMBL23607511 | 0.87 | ACHE (0.66) | ACHEEPHX1 | |
| SCHEMBL30080469 | 0.84 | ACHE (0.51) | ACHEEPHX1EPHX2 | |
| SCHEMBL19513091 | 0.84 | ACHE (0.58) | ACHEEPHX1EPHX2 | |
| SCHEMBL30080289 | 0.83 | ACHE (0.54) | ACHEEPHX1EPHX2 | |
| SCHEMBL31290254 | 0.83 | ACHE (0.47) | ACHEEPHX2 | |
| SCHEMBL24758685 | 0.83 | GLA (0.41) | ACHE | |
| SCHEMBL23138402 | 0.83 | ACHE (0.46) | ACHE | |
| SCHEMBL19513165 | 0.80 | EPHX2 (0.51) | ACHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2875017-A1 | DERIVATIVES OF 1-(SUBSTITUTED SULFONYL)-2-AMINOIMIDAZOLINE AS ANTITUMOR AND ANTIPROLIFERATIVE AGENTS | ONCOARENDI THERAPEUTICS SP. Z.O.O. (PL) | 2015-05-27 | — | — | EP | disclosed |
| WO-2014167446-A1 | DERIVATIVES OF 1-(SUBSTITUTED SULFONYL)-2-AMINOIMIDAZOLINE AS ANTITUMOR AND ANTIPROLIFERATIVE AGENTS | OncoArendi Therapeutics Sp. z o.o. (PL) | 2014-10-16 | — | — | WO | disclosed |