Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 14/20 | 0.60 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16166336 | 0.92 | ACHE (0.57) | ACHEEPHX2EPHX1 | |
| SCHEMBL23607511 | 0.89 | ACHE (0.66) | ACHEEPHX1 | |
| SCHEMBL22381321 | 0.87 | ACHE (0.55) | ACHEEPHX2EPHX1 | |
| SCHEMBL23137391 | 0.87 | ACHE (0.51) | ACHEEPHX2EPHX1 | |
| SCHEMBL19513091 | 0.86 | ACHE (0.58) | ACHEEPHX2EPHX1 | |
| SCHEMBL30080469 | 0.86 | ACHE (0.51) | ACHEEPHX2EPHX1 | |
| SCHEMBL16013082 | 0.85 | ACHE (0.51) | ACHEEPHX2EPHX1 | |
| SCHEMBL30080289 | 0.85 | ACHE (0.54) | ACHEEPHX2EPHX1 | |
| SCHEMBL25810088 | 0.85 | ACHE (0.51) | ACHE | |
| SCHEMBL31290254 | 0.82 | ACHE (0.47) | ACHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11639342-B2 | 1,3-dipolar cycloadditions, and Staudinger ligations for conjugating biomolecules using click chemistry | Bioconjugate Technologies, LLC (US) | 2023-05-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11639342-B2 | 1,3-dipolar cycloadditions, and Staudinger ligations for conjugating biomolecules using click chemistry | LIG1, TIE1, ALDH1B1 | ACHE 816/4885EPHX2 767/4885EPHX1 1278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.