Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 11/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.41 |
| ▸ | NQO2 | P16083 | 8/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16167698 | 0.87 | PPARD (0.49) | MTNR1A | |
| SCHEMBL1207292 | 0.85 | MTNR1A (0.41) | MTNR1AMTNR1BNQO2MIF | |
| Hydrochloric Acid SCHEMBL1206117 | 0.84 | MTNR1A (0.41) | MTNR1AMTNR1BNQO2MIF | |
| SCHEMBL4260242 | 0.80 | MTNR1A (0.65) | MTNR1AMTNR1BNQO2 | |
| Hydrochloric Acid SCHEMBL1396530 | 0.80 | PPARD (0.43) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL4264345 | 0.78 | MTNR1A (0.66) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL4259220 | 0.77 | MTNR1A (0.50) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL4264832 | 0.77 | MTNR1A (0.54) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL4258217 | 0.76 | MTNR1A (0.67) | MTNR1AMTNR1BNQO2 | |
| SCHEMBL13891904 | 0.75 | HTR2A (0.40) | MTNR1AMTNR1BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859580-B2 | Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-10-14 | — | — | US | disclosed |