Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 8/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16167706 | 0.87 | MTNR1A (0.42) | MTNR1A | |
| SCHEMBL1206528 | 0.84 | PPARD (0.48) | PPARDATMFFAR1PTGDR2PPARA | |
| Hydrochloric Acid SCHEMBL1207635 | 0.83 | PPARD (0.47) | PPARDATMFFAR1PTGDR2PPARA | |
| SCHEMBL4260242 | 0.79 | MTNR1A (0.65) | MTNR1A | |
| Hydrochloric Acid SCHEMBL1396530 | 0.78 | PPARD (0.43) | PPARDATMFFAR1PTGDR2PPARA | |
| SCHEMBL31326550 | 0.77 | TP53 (0.41) | PPARDATMFFAR1PPARG | |
| SCHEMBL21978182 | 0.77 | TP53 (0.41) | PPARDATMFFAR1PPARG | |
| SCHEMBL4264345 | 0.77 | MTNR1A (0.66) | MTNR1A | |
| SCHEMBL13891904 | 0.77 | HTR2A (0.40) | MTNR1A | |
| SCHEMBL9467265 | 0.77 | MTNR1A (0.52) | PPARDMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859580-B2 | Aryl- and heteroarylcarbonyl derivatives of benzomorphanes and related scaffolds, medicaments containing such compounds and their use | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-10-14 | — | — | US | disclosed |