Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GLP1R | P43220 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16167810 | 1.00 | ADRA1A (0.49) | ADRA1AEPHX2TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL16167785 | 1.00 | ADRA1A (0.49) | ADRA1AEPHX2TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL16167791 | 1.00 | ADRA1A (0.49) | ADRA1AEPHX2TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL16167792 | 1.00 | ADRA1A (0.49) | ADRA1AEPHX2TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL14118080 | 0.97 | ADRA1A (0.49) | ADRA1AEPHX2TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL15196467 | 0.94 | TSHR (0.47) | ADRA1AEPHX2TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL17929791 | 0.94 | TSHR (0.47) | ADRA1AEPHX2TSHRKDM4ESMN1; SMN2 | |
| SCHEMBL14118030 | 0.92 | ADRA1A (0.46) | ADRA1AEPHX2TSHRKDM4EPRMT1 | |
| SCHEMBL16167809 | 0.92 | ADRA1A (0.46) | ADRA1AEPHX2TSHRKDM4EPRMT1 | |
| SCHEMBL16167787 | 0.91 | ADRA1A (0.46) | ADRA1AEPHX2TSHRKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859493-B2 | Insulin derivatives | NOVO NORDISK A/S (DK) | 2014-10-14 | — | — | US | disclosed |