SCHEMBL16168569

SCHEMBL16168569

c1ccc(-c2ccc3c(c2)c2cc(-c4ccc5c(c4)[nH]c4ccccc45)ccc2n3-c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.43
AHR P35869 1/20 0.43
KDM4E B2RXH2 1/20 0.43
ATM Q13315 1/20 0.43
FEN1 P39748 1/20 0.43
TNKS2 Q9H2K2 1/20 0.42
KIF11 P52732 7/20 0.42
PDE7A Q13946 2/20 0.41
PDE7B Q9NP56 2/20 0.41
CDK4 P11802 2/20 0.40
CCND1 P24385 2/20 0.40
ALDH1A1 P00352 1/20 0.40
GPR3 P46089 1/20 0.40
HSD17B10 Q99714 1/20 0.40
JAK2 O60674 1/20 0.38
MEN1 O00255 1/20 0.38
LMNA P02545 1/20 0.38
KMT2A Q03164 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16727275 0.97 AHR (0.43) L3MBTL1AHRKDM4EATMFEN1
SCHEMBL15199680 0.96 L3MBTL1 (0.50) L3MBTL1AHRKDM4EATMFEN1
SCHEMBL14212469 0.94 KDM4E (0.45) L3MBTL1AHRKDM4EATMFEN1
SCHEMBL29506377 0.94 L3MBTL1 (0.51) L3MBTL1AHRKDM4EATMFEN1
SCHEMBL9891302 0.94 L3MBTL1 (0.51) L3MBTL1AHRKDM4EATMFEN1
SCHEMBL15589128 0.93 KDM4E (0.47) L3MBTL1AHRKDM4EATMFEN1
SCHEMBL10042449 0.93 KDM4E (0.44) L3MBTL1AHRKDM4EATMKIF11
SCHEMBL18705983 0.92 L3MBTL1 (0.46) L3MBTL1AHRKDM4EATMFEN1
SCHEMBL18185665 0.92 KDM4E (0.42) L3MBTL1AHRKDM4EATMFEN1
SCHEMBL18705596 0.92 L3MBTL1 (0.46) L3MBTL1AHRKDM4EATMFEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2790239-B1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT IDEMITSU KOSAN CO (JP) 2020-02-05 EP disclosed
US-9306171-B2 Material for organic electroluminescence device and organic electroluminescence device IDEMITSU KOSAN CO., LTD. (JP) 2016-04-05 US disclosed
EP-2790239-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENT AND ORGANIC ELECTROLUMINESCENT ELEMENT Idemitsu Kosan Co., Ltd (JP) 2014-10-15 EP disclosed