Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | GAPDH | P04406 | 1/20 | 0.52 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10022355 | 0.87 | MAPT (0.52) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL17464564 | 0.84 | CA12 (0.68) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL17458754 | 0.84 | CA12 (0.68) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL15213476 | 0.82 | USP7 (0.77) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5521706 | 0.79 | MAPT (0.54) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL5522483 | 0.79 | MAPT (0.54) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL16406026 | 0.76 | MAPT (0.53) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL14979491 | 0.76 | CYBB (0.84) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL16406038 | 0.76 | CYBB (0.55) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL16406025 | 0.76 | MAPT (0.61) | MAPTKDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2590950-B1 | N-CYCLYL-3-(CYCLYLCARBONYLAMINOMETHYL)BENZAMIDE DERIVATIVES AS RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2014-10-15 | — | — | EP | disclosed |