Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14231470 | 0.98 | KMT2A (0.62) | MEN1KMT2AATMCYP2D6CYP2C19 | |
| SCHEMBL11118757 | 0.81 | MEN1 (1.00) | MEN1KMT2AATMCYP2D6CYP2C19 | |
| SCHEMBL11480838 | 0.81 | MEN1 (0.64) | MEN1KMT2AATMCYP2D6CYP2C19 | |
| SCHEMBL3060825 | 0.81 | MEN1 (0.64) | MEN1KMT2AATMCYP2D6CYP2C19 | |
| SCHEMBL68147 | 0.81 | KMT2A (0.64) | MEN1KMT2AATMCYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL29215641 | 0.79 | KMT2A (0.61) | MEN1KMT2AATMCYP2D6CYP2C19 | |
| SCHEMBL20027940 | 0.78 | KMT2A (0.60) | MEN1KMT2AATMCYP2D6CYP2C19 | |
| SCHEMBL14116880 | 0.78 | KMT2A (0.60) | MEN1KMT2AATMCYP2D6CYP2C19 | |
| SCHEMBL67311 | 0.78 | KMT2A (0.60) | MEN1KMT2AATMCYP2D6CYP2C19 | |
| SCHEMBL14538079 | 0.78 | KMT2A (0.60) | MEN1KMT2AATMCYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1911761-B1 | WATER-SOLUBLE ARTEMISININ DERIVATIVES, THEIR PREPARATION METHODS, THE PHARMACEUTICAL COMPOSITIONS AND THE USE THEREOF | SHANGHAI INST MATERIA MEDICA (CN) | 2014-10-15 | — | — | EP | disclosed |