SCHEMBL67311

SCHEMBL67311

COCC(O)CN1CCCC1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.60
MEN1 O00255 2/20 0.60
ATM Q13315 2/20 0.56
KDM4E B2RXH2 2/20 0.56
POLB P06746 2/20 0.56
MAPT P10636 1/20 0.56
CYP2D6 P10635 2/20 0.53
CYP2C19 P33261 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.50
TSHR P16473 1/20 0.50
HIF1A Q16665 1/20 0.50
HTT P42858 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
ACE2 Q9BYF1 1/20 0.49
ABCB1 P08183 1/20 0.46
ALDH1A1 P00352 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14116880 1.00 KMT2A (0.60) KMT2AMEN1ATMKDM4EPOLB
SCHEMBL20027940 1.00 KMT2A (0.60) KMT2AMEN1ATMKDM4EPOLB
SCHEMBL68147 0.98 KMT2A (0.64) KMT2AMEN1ATMKDM4EPOLB
SCHEMBL14355276 0.96 KMT2A (0.54) KMT2AMEN1ATMKDM4EPOLB
SCHEMBL14116870 0.96 KMT2A (0.54) KMT2AMEN1ATMKDM4EPOLB
SCHEMBL9621208 0.91 KDM4E (0.50) KMT2AMEN1ATMKDM4EPOLB
SCHEMBL3969316 0.91 KDM4E (0.50) KMT2AMEN1ATMKDM4EPOLB
SCHEMBL8283447 0.84 USP2 (0.58) KMT2AMEN1POLBCYP2D6CYP2C19
SCHEMBL23657255 0.83 KDM4E (0.62) KMT2AMEN1KDM4EPOLBMAPT
SCHEMBL23657198 0.83 KDM4E (0.62) KMT2AMEN1KDM4EPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250262589-A1 AMINE COMPOSITION FOR CARBON DIOXIDE SEPARATION USE TOSOH CORPORATION (JP) 2025-08-21 US disclosed
EP-4494740-A1 AMINE COMPOSITION FOR CARBON DIOXIDE SEPARATION USE TOSOH CORPORATION (JP) 2025-01-22 EP disclosed
CN-119095662-A Amine composition for separating carbon dioxide 东曹株式会社 2024-12-06 CN disclosed
EP-3442947-B1 AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS AS EHMT1 AND EHMT2 INHIBITORS EPIZYME INC (US) 2023-06-07 EP disclosed
EP-4105203-A1 SPIRO-CONDENSED INDOLE COMPOUNDS AS EHMT2 INHIBITORS Epizyme Inc (US) 2022-12-21 EP disclosed
CN-114901383-A Composition for separating carbon dioxide and method for separating carbon dioxide 东曹株式会社 2022-08-12 CN disclosed
EP-3519393-B1 SUBSTITUTED FUSED BI- OR TRI- HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS EPIZYME INC (US) 2022-05-18 EP disclosed
US-20200317642-A1 AMINE-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS AND DERIVATIVES THEREOF Epizyme, Inc. 2020-10-08 US disclosed
WO-2018064557-A1 SUBSTITUTED FUSED BI- OR TRI- HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS Epizyme, Inc. (US) 2018-04-05 WO disclosed
US-20170355712-A1 AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS Epizyme, Inc. 2017-12-14 US disclosed
US-9301923-B2 Lipids, lipid compositions, and methods of using them NOVARTIS AG (CH) 2016-04-05 US disclosed
US-20140309277-A1 LIPIDS, LIPID COMPOSITIONS, AND METHODS OF USING THEM NOVARTIS AG (CH) 2014-10-16 US disclosed
US-8129426-B2 Water-soluble artemisinin derivatives, their preparation methods, the pharmaceutical compositions and the use thereof SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2012-03-06 US disclosed
US-20110200582-A1 LIPIDS, LIPID COMPOSITIONS, AND METHODS OF USING THEM NOVARTIS AG (CH) 2011-08-18 US disclosed
WO-2011076807-A2 LIPIDS, LIPID COMPOSITIONS, AND METHODS OF USING THEM NOVARTIS AG (CH) 2011-06-30 WO disclosed
US-7795440-B2 N-substituted tricyclic 1-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders JANSSEN PHARMACEUTICA NV (BE) 2010-09-14 US disclosed
US-20090298881-A1 Water-Soluble Artemisinin Derivatives, Their Preparation Methods, the Pharmaceutical Compositions and the Use Thereof JIANGSU ZUOYOU MEDICINE CO., LTD. (CN) 2009-12-03 US disclosed
US-7312235-B2 Benzamide inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-12-25 US disclosed
US-7312235-B2 Benzamide inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-12-25 US disclosed
US-20070142305-A1 N-substituted tricyclic 1-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders HO CHIH Y 2007-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110200582-A1 LIPIDS, LIPID COMPOSITIONS, AND METHODS OF USING THEM SGMS1, SGMS2, LIPC KMT2A 4503/4885MEN1 608/4885ATM 4808/4885
US-20170355712-A1 AMINE-SUBSTITUTED ARYL OR HETEROARYL COMPOUNDS SHMT1, BHMT, BHMT2 KMT2A 17/4885MEN1 3483/4885ATM 2188/4885
US-20140309277-A1 LIPIDS, LIPID COMPOSITIONS, AND METHODS OF USING THEM SGMS1, SGMS2, LIPC KMT2A 4503/4885MEN1 608/4885ATM 4808/4885
US-20200317642-A1 AMINE-SUBSTITUTED HETEROCYCLIC COMPOUNDS AS EHMT2 INHIBITORS AND DERIVATIVES THEREOF HNMT, EHMT2, SHMT2 KMT2A 29/4885MEN1 1356/4885ATM 555/4885
US-20070142305-A1 N-substituted tricyclic 1-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders PDGFRA, PDGFRB, PDGFA KMT2A 2557/4885MEN1 2796/4885ATM 1151/4885
US-20090298881-A1 Water-Soluble Artemisinin Derivatives, Their Preparation Methods, the Pharmaceutical Compositions and the Use Thereof NFATC1, THPO, SQLE KMT2A 4018/4885MEN1 2419/4885ATM 1940/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.