SCHEMBL68147

SCHEMBL68147

COCC(O)CN1CCCCC1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.64
MEN1 O00255 1/20 0.64
KDM4E B2RXH2 2/20 0.58
POLB P06746 1/20 0.58
ATM Q13315 2/20 0.58
CYP2D6 P10635 2/20 0.56
CYP2C19 P33261 1/20 0.56
MAPT P10636 1/20 0.54
TSHR P16473 2/20 0.53
HIF1A Q16665 1/20 0.53
ACE2 Q9BYF1 1/20 0.51
ABCB1 P08183 4/20 0.49
ALDH1A1 P00352 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
HSD17B10 Q99714 1/20 0.48
HTT P42858 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14116880 0.98 KMT2A (0.60) KMT2AMEN1KDM4EPOLBATM
SCHEMBL67311 0.98 KMT2A (0.60) KMT2AMEN1KDM4EPOLBATM
SCHEMBL20027940 0.98 KMT2A (0.60) KMT2AMEN1KDM4EPOLBATM
SCHEMBL14355276 0.94 KMT2A (0.54) KMT2AMEN1KDM4EPOLBATM
SCHEMBL14116870 0.94 KMT2A (0.54) KMT2AMEN1KDM4EPOLBATM
SCHEMBL9621208 0.89 KDM4E (0.50) KMT2AMEN1KDM4EPOLBATM
SCHEMBL3969316 0.89 KDM4E (0.50) KMT2AMEN1KDM4EPOLBATM
SCHEMBL8283447 0.82 USP2 (0.58) KMT2AMEN1POLBCYP2D6CYP2C19
SCHEMBL23706771 0.82 ALDH1A1 (0.55) KMT2AMEN1KDM4EPOLBMAPT
SCHEMBL23657198 0.82 KDM4E (0.62) KMT2AMEN1KDM4EPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250262589-A1 AMINE COMPOSITION FOR CARBON DIOXIDE SEPARATION USE TOSOH CORPORATION (JP) 2025-08-21 US disclosed
EP-4494740-A1 AMINE COMPOSITION FOR CARBON DIOXIDE SEPARATION USE TOSOH CORPORATION (JP) 2025-01-22 EP disclosed
CN-119095662-A Amine composition for separating carbon dioxide 东曹株式会社 2024-12-06 CN disclosed
CN-114901383-A Composition for separating carbon dioxide and method for separating carbon dioxide 东曹株式会社 2022-08-12 CN disclosed
WO-2021153650-A1 COMPOSITION FOR CARBON DIOXIDE SEPARATION AND METHOD FOR SEPARATING CARBON DIOXIDE 東ソー株式会社 2021-08-05 WO disclosed
US-8946444-B2 Tetrahydrocarbazoles as active agents for inhibiting VEGF production by translational control PTC THERAPEUTICS, INC. (US) 2015-02-03 US disclosed
US-8129426-B2 Water-soluble artemisinin derivatives, their preparation methods, the pharmaceutical compositions and the use thereof SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES (CN) 2012-03-06 US disclosed
US-7745641-B2 Nitrogen-containing heterocyclic compound KYOWA HAKKO KIRIN CO., LTD. (JP) 2010-06-29 US disclosed
US-7745641-B2 Nitrogen-containing heterocyclic compound KYOWA HAKKO KIRIN CO., LTD. (JP) 2010-06-29 US disclosed
US-20090298881-A1 Water-Soluble Artemisinin Derivatives, Their Preparation Methods, the Pharmaceutical Compositions and the Use Thereof JIANGSU ZUOYOU MEDICINE CO., LTD. (CN) 2009-12-03 US disclosed
US-20090054407-A1 Nitrogen-containing heterocyclic compound KYOWA HAKKO KOGYO CO., LTD. (JP) 2009-02-26 US disclosed
US-20090054407-A1 Nitrogen-containing heterocyclic compound KYOWA HAKKO KOGYO CO., LTD. (JP) 2009-02-26 US disclosed
US-20090042866-A1 Tetrahydrocarbazoles as Active Agents for Inhibiting VEGF Production by Translational Control PTC THERAPEUTICS, INC. 2009-02-12 US disclosed
US-7312235-B2 Benzamide inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-12-25 US disclosed
US-7312235-B2 Benzamide inhibitors of factor Xa MILLENNIUM PHARMACEUTICALS, INC. (US) 2007-12-25 US disclosed
US-20070142305-A1 N-substituted tricyclic 1-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders HO CHIH Y 2007-06-21 US disclosed
US-7196110-B2 N-substituted tricyclic 3-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders JANSSEN PHAMACEUTICA N.V. (BE) 2007-03-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090054407-A1 Nitrogen-containing heterocyclic compound NR4A1, NR5A2, PRMT8 KMT2A 320/4885MEN1 1165/4885KDM4E 488/4885
US-20090042866-A1 Tetrahydrocarbazoles as Active Agents for Inhibiting VEGF Production by Translational Control VEGFA, FLT4, KDR KMT2A 3806/4885MEN1 4608/4885KDM4E 518/4885
US-20070142305-A1 N-substituted tricyclic 1-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders PDGFRA, PDGFRB, PDGFA KMT2A 2557/4885MEN1 2796/4885KDM4E 2367/4885
US-20090298881-A1 Water-Soluble Artemisinin Derivatives, Their Preparation Methods, the Pharmaceutical Compositions and the Use Thereof NFATC1, THPO, SQLE KMT2A 4018/4885MEN1 2419/4885KDM4E 3498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.