SCHEMBL16169474

SCHEMBL16169474

CC1(C)c2cc(-c3c4ccccc4c(-c4ccc(C#N)cc4)c4ccccc34)cc3ccc4cc(-c5c6ccccc6c(-c6ccc(C#N)cc6)c6ccccc56)cc1c4c23

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A12 Q96S37 1/20 0.37
CA1 P00915 2/20 0.37
CA2 P00918 2/20 0.37
PGR P06401 3/20 0.35
PDK2 Q15119 1/20 0.35
TNKS O95271 1/20 0.35
ABCB1 P08183 1/20 0.34
ABCG2 Q9UNQ0 1/20 0.34
PDPK1 O15530 1/20 0.34
ACP1 P24666 1/20 0.34
HRH3 Q9Y5N1 2/20 0.34
ATM Q13315 2/20 0.33
GABRA1 P14867 1/20 0.33
GABRG2 P18507 1/20 0.33
GABRB3 P28472 1/20 0.33
GABRA5 P31644 1/20 0.33
GABRA3 P34903 1/20 0.33
CYP17A1 P05093 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13170823 0.78 PDK2 (0.49) SLC22A12PGRPDK2TNKSACP1
SCHEMBL16169472 0.78 ESR1 (0.40) TNKSACP1
SCHEMBL15424283 0.78 ABCG2 (0.44) ABCB1ABCG2GABRA1GABRG2GABRB3
SCHEMBL15763478 0.78 CA1 (0.40) CA1CA2PGRPDK2CYP17A1
SCHEMBL15763488 0.78 PDK2 (0.41) CA1CA2PGRPDK2HRH3
SCHEMBL15909652 0.77 MYC (0.39) PGRPDK2ABCG2HRH3GABRA1
SCHEMBL15763489 0.77 PDK2 (0.40) CA1CA2PGRPDK2CYP17A1
SCHEMBL13488065 0.77 PDK2 (0.43) SLC22A12CA1CA2PGRPDK2
SCHEMBL16168911 0.77 KDM4E (0.35) ALDH1A1
SCHEMBL15907508 0.77 PGR (0.39) PGRPDK2HRH3GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9548456-B2 Organic compound and organic light emitting diode device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-01-17 US disclosed
US-20140306190-A1 ORGANIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2014-10-16 US disclosed