SCHEMBL15907508

SCHEMBL15907508

CC1(C)c2cc(Br)cc3ccc4cc(-c5ccc(C#N)cc5)cc1c4c23

nearest known ligand 0.39

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PGR P06401 6/20 0.39
HRH3 Q9Y5N1 7/20 0.37
ESR1 P03372 1/20 0.37
ESR2 Q92731 1/20 0.37
KIF11 P52732 1/20 0.35
MMP3 P08254 1/20 0.34
PDK2 Q15119 1/20 0.33
RIPK1 Q13546 1/20 0.33
GAA P10253 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15424265 0.82 MYC (0.38) PGRHRH3ESR1ESR2PDK2
SCHEMBL15316881 0.81 ALDH1A1 (0.35) ESR1ESR2
SCHEMBL15424283 0.79 ABCG2 (0.44)
SCHEMBL15909678 0.78 LPL (0.43) ESR1ESR2
SCHEMBL1698290 0.78 NPSR1 (0.35)
SCHEMBL15909652 0.78 MYC (0.39) PGRHRH3PDK2
SCHEMBL16169474 0.77 SLC22A12 (0.37) PGRHRH3PDK2GAA
SCHEMBL17849691 0.75 ALDH1A1 (0.48) ESR1ESR2
SCHEMBL17849647 0.74 MYC (0.37) PGRHRH3PDK2
SCHEMBL15909665 0.74 HRH3 (0.35) PGRHRH3PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9773987-B2 Silicon-based compound and organic light-emitting diode comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-09-26 US disclosed
US-9773987-B2 Silicon-based compound and organic light-emitting diode comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2017-09-26 US disclosed
US-20140209869-A1 SILICON-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD (KR) 2014-07-31 US disclosed
US-20140209869-A1 SILICON-BASED COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING THE SAME SAMSUNG DISPLAY CO., LTD (KR) 2014-07-31 US disclosed