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SCHEMBL1616948

SCHEMBL1616948

CN(C)c1ccc(C(=CC2(C=C(c3ccc(N(C)C)cc3)c3ccc(N(C)C)cc3)OC(=O)c3ccc(N4CCCC4)cc32)c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 9/20 0.36
▸ HPGD P15428 6/20 0.36
▸ HSD17B10 Q99714 5/20 0.36
▸ TDP1 Q9NUW8 3/20 0.36
▸ CYP3A4 P08684 1/20 0.36
▸ HIF1A Q16665 1/20 0.36
▸ RAB9A P51151 7/20 0.35
▸ MAPT P10636 6/20 0.35
▸ NPC1 O15118 5/20 0.35
▸ L3MBTL1 Q9Y468 4/20 0.35
▸ ALOX15 P16050 3/20 0.35
▸ LMNA P02545 2/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ TP53 P04637 2/20 0.35
▸ TSHR P16473 2/20 0.35
▸ STAT1 P42224 1/20 0.35
▸ PDK2 Q15119 3/20 0.35
▸ HTT P42858 2/20 0.35
▸ USP2 O75604 1/20 0.35
▸ POLB P06746 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1618125 0.93 ALDH1A1 (0.40) ALDH1A1HPGDHSD17B10TDP1CYP3A4
SCHEMBL9557823 0.93 RAB9A (0.37) ALDH1A1HPGDHSD17B10TDP1CYP3A4
SCHEMBL1618209 0.90 ALDH1A1 (0.43) ALDH1A1HPGDHSD17B10TDP1RAB9A
SCHEMBL1618378 0.88 ALDH1A1 (0.42) ALDH1A1HPGDHSD17B10TDP1CYP3A4
SCHEMBL9663554 0.86 MAPT (0.38) ALDH1A1HPGDHSD17B10TDP1CYP3A4
SCHEMBL9663559 0.86 MAPT (0.38) ALDH1A1HPGDHSD17B10TDP1CYP3A4
SCHEMBL1618101 0.85 ALDH1A1 (0.46) ALDH1A1HPGDHSD17B10TDP1CYP3A4
SCHEMBL1617907 0.84 MAPT (0.40) ALDH1A1HPGDHSD17B10RAB9AMAPT
SCHEMBL1617727 0.82 ALDH1A1 (0.43) ALDH1A1HPGDHSD17B10TDP1RAB9A
SCHEMBL1617795 0.82 ALDH1A1 (0.40) ALDH1A1HPGDHSD17B10TDP1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7923488-B2 Leuco dyes with a N,N-dialkylamino, N,N-diarylamino, N-alkyl-N-arylamino, N-alkylamino, or N-arylamino group on one of the aromatic rings and a latent curing agent or catalyst activate-able by heat, pressure, or radiation TRILLION SCIENCE, INC. (US) 2011-04-12 — — US disclosed
US-20080090943-A1 Leuco dyes with a N,N-dialkylamino, N,N-diarylamino, N-alkyl-N-arylamino, N-alkylamino, or N-arylamino group on one of the aromatic rings and a latent curing agent or catalyst activate-able by heat, pressure, or radiation TRILLION, INC. 2008-04-17 — — US disclosed
US-5242884-A Storage stability, antioxidant, secondary amine, basic dye KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1993-09-07 — — US disclosed
EP-0232907-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1991-03-27 — — EP disclosed
EP-0196484-B1 PRESSURE SENSITIVE MANIFOLD SHEET KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1990-05-09 — — EP disclosed
US-4761396-A BASIC PHTHALIDE DYE REACTS WITH FLUORENE DERIVATIVE AND P-PHENYLENEDIAMINE DERIVATIVE KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1988-08-02 — — US disclosed
US-4704379-A Pressure sensitive manifold sheet KANZAKI PAPER MANUFACTURING CO. LTD. (JP) 1987-11-03 — — US disclosed
EP-0196484-A1 Pressure sensitive manifold sheet KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1986-10-08 — — EP disclosed
US-4580153-A COLOR FORMING BETWEEN COLORLESS CHROMOGENIC VINYL PHTHALIDE COMPOUND AND ELECTRON ACCEPTOR KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1986-04-01 — — US disclosed